Evidence map›Paper›PMID 41144571›Full record

ArticlePloS one2025

"I just thought I was lucky to be protected from HIV:" Qualitative evaluation of barriers and facilitators of pre-exposure prophylaxis use for adolescent girls and young women at higher risk of HIV acquisition in Lilongwe, Malawi.

Mallory Michalak, Odala Sande, Sam Phiri, Hannock Tweya, Geldert Chiwaya, Joseph Chintedza, Beatrice Matanje, Christine Kiruthu-Kamamia, Jacqueline Huwa, Jane Chiwoko and 15 more

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Mallory MichalakUnited States Centers for Disease Control and Prevention, Division of Global HIV and Tuberculosis, Atlanta, Georgia, United States of America.ORCID https://orcid.org/0000-0002-4993-8871
Odala SandeUnited States Centers for Disease Control and Prevention, Division of Global HIV and Tuberculosis, Lilongwe, Malawi.
Sam PhiriUnited States Centers for Disease Control and Prevention, Division of Global HIV and Tuberculosis, Lilongwe, Malawi.ORCID https://orcid.org/0000-0002-9372-212X
Hannock TweyaUnited States Centers for Disease Control and Prevention, Division of Global HIV and Tuberculosis, Lilongwe, Malawi.
Geldert ChiwayaUnited States Centers for Disease Control and Prevention, Division of Global HIV and Tuberculosis, Lilongwe, Malawi.
Joseph ChintedzaUnited States Centers for Disease Control and Prevention, Division of Global HIV and Tuberculosis, Lilongwe, Malawi.
Beatrice MatanjeUnited States Centers for Disease Control and Prevention, Division of Global HIV and Tuberculosis, Lilongwe, Malawi.
Christine Kiruthu-KamamiaUnited States Centers for Disease Control and Prevention, Division of Global HIV and Tuberculosis, Lilongwe, Malawi.
Jacqueline HuwaUnited States Centers for Disease Control and Prevention, Division of Global HIV and Tuberculosis, Lilongwe, Malawi.ORCID https://orcid.org/0000-0001-8786-2487
Jane ChiwokoUnited States Centers for Disease Control and Prevention, Division of Global HIV and Tuberculosis, Lilongwe, Malawi.
Tom ChawezaUnited States Centers for Disease Control and Prevention, Division of Global HIV and Tuberculosis, Lilongwe, Malawi.
Rose NyirendaLighthouse Trust, Lilongwe, Malawi.
Thokozani KaluaUnited States Centers for Disease Control and Prevention, Division of Global HIV and Tuberculosis, Lilongwe, Malawi.
Andreas JahnLighthouse Trust, Lilongwe, Malawi.
Alinafe MbeweLighthouse Trust, Lilongwe, Malawi.
Alice MaidaMinistry of Health, Lilongwe, Malawi.
Evelyn KimUnited States Centers for Disease Control and Prevention, Division of Global HIV and Tuberculosis, Atlanta, Georgia, United States of America.
Wezi MsungamaMinistry of Health, Lilongwe, Malawi.
Fatima ZuluMinistry of Health, Lilongwe, Malawi.
Mtemwa NyanguluMinistry of Health, Lilongwe, Malawi.
Sarah ShawRWD Consulting, LLC, Seattle, Washington, United States of America.ORCID https://orcid.org/0000-0002-3517-0881
Victor SinganoMinistry of Health, Lilongwe, Malawi.ORCID https://orcid.org/0000-0002-2671-7291
Newton KalataMinistry of Health, Lilongwe, Malawi.
Alinune KabagheMinistry of Health, Lilongwe, Malawi.
Pragna PatelUnited States Centers for Disease Control and Prevention, Division of Global HIV and Tuberculosis, Atlanta, Georgia, United States of America.

Funding

Malawi HIV Implementation Research Scientist Training Program (MHIRST)D43TW010060 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MINA CHRISTINE HOSSEINIPOUR, Victor Mwapasa · 2015 to 2026
$3.8M
FIC NIH HHS D43 TW010060
6 · The paper itself

Abstract

Adolescent girls and young women (AGYW) are at higher risk of HIV acquisition than their male counterparts, especially in sub-Saharan African countries such as Malawi. Therefore, HIV prevention programming is a key component to reducing this risk. We conducted a formative qualitative assessment with AGYW and their health providers to understand AGYW's perceptions of their own HIV risk, self-efficacy to protect themselves, and the implications of these factors on pre-exposure prophylaxis (PrEP) use. Our study found that AGYW are aware and interested in using PrEP, which can allow choices that protect their sexual health and well-being. Innovative service delivery models that minimize stigma and offer other reproductive health services such as contraception are needed to provide comprehensive care. Additionally, AGYW and their health providers would benefit from education about HIV risk perception and PrEP effectiveness to improve use of PrEP. Robust AGYW PrEP service delivery, including new biomedical prevention strategies, may facilitate efforts to achieve epidemic control.

Indexed as

HIV InfectionsPre-Exposure ProphylaxisAdolescentAdultAnti-HIV AgentsFemaleHealth Knowledge, Attitudes, PracticeHumansMalawiMaleYoung AdultAnti-HIV Agents

Identifiers

PMID41144571
PMCPMC12558490

What OpenQuestion holds

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LicenceCC0
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.