ReviewAdipocyte2025
Crosstalk between microRNAs and autophagy in adipocyte differentiation: emerging therapeutic targets for obesity.
Review in Adipocyte, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Identification of Candidate miRNAs Associated with Shear Force and Intramuscular Fat in Pig Breeds.Foods (Basel, Switzerland) · 2026Article
- MicroRNA-Mediated Regulation of Brain Aging Hallmarks: Implications for Neurodegeneration and Neural Recovery.Brain and behavior · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity remains a global health challenge, underscoring the need for more effective therapeutic strategies. Recent evidence highlights the central role of adipose tissue autophagy in metabolic homoeostasis, with its dysregulation contributing to obesity-related pathophysiology. MicroRNAs (miRNAs) have emerged as critical regulators of autophagy in adipocytes, influencing differentiation, lipid metabolism, and systemic energy balance. This review synthesizes current knowledge on how specific miRNAs modulate autophagic activity in adipose tissue and discusses their functional impact on adipocyte biology. Based on the accumulated evidence, we conclude that targeting miRNA-mediated autophagy pathways holds significant therapeutic potential for obesity and related metabolic disorders. Future research should focus on translating these mechanistic insights into targeted interventions, overcoming delivery challenges, and advancing miRNA-based therapeutics towards clinical application.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.