Evidence map›Paper›PMID 41144225›Full record

ArticleDigestive diseases and sciences2026

Efficacy of Endoscopic Full Thickness Resection Using the Full-Thickness Resection Device for Submucosal Invasive Colorectal Cancer: The First United States Multicenter Experience.

Rahul Karna, Syed Kashif Mahmood, Jennifer Phan, Sumant Inamdar, Antonio Mendoza Ladd, Veeral M Oza, Mohit Girotra, Harshit Khara, Natalie Wilson, Nabeel Azeem and 1 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Digestive diseases and sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Optimizing detection and resection of colorectal polyps.Translational gastroenterology and hepatology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rahul KarnaDivision of Gastroenterology & Hepatology, University of Minnesota Medical Center, Minneapolis, MN, USA.
Syed Kashif MahmoodDivision of Gastroenterology & Hepatology, Lahey Hospital and Medical Center, Burlington, MA, USA.
Jennifer PhanHoag Digestive Health Institute, Newport, CA, USA.
Sumant InamdarDivision of Gastroenterology & Hepatology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Antonio Mendoza LaddDivision of Gastroenterology & Hepatology, University of California Davis Health, Sacramento, CA, USA.
Veeral M OzaDivision of Gastroenterology & Hepatology, Bon Secours Mercy Health, Greenville, SC, USA.
Mohit GirotraDigestive Health Institute, Swedish Medical Center, Seattle, WA and Elson S. Floyd School of Medicine, Washington State University, Pullman, WA, USA.
Harshit KharaDivision of Gastroenterology & Hepatology, Geisinger Medical Center, Danville, PA, USA.
Natalie WilsonDepartment of Internal Medicine, University of Minnesota Medical Center, Minneapolis, MN, USA.
Nabeel AzeemDivision of Gastroenterology & Hepatology, University of Minnesota Medical Center, Minneapolis, MN, USA.
Mohammad BilalDivision of Gastroenterology & Hepatology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. billa17@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEndoscopic full-thickness resection (EFTR) using full thickness resection device is used for removal of non-lifting or previously manipulated polyps. There is limited data regarding its efficacy for removal of colorectal submucosal invasive cancer (SMIC).

methodsWe conducted retrospective multicenter study on patients who underwent EFTR using full thickness resection device for suspected or biopsy proven colorectal cancer (CRC).

resultsTechnical success was 100% and R0 resection rate was 85%. Overall, 6/20 were referred for surgery due to high risk features. Curative resection rate was 46.7% (7/15) in T1 CRC. Adverse events included 1 bleeding and 1 perforation, managed endoscopically and 1 bleeding and 2 post-polypectomy syndromes managed conservatively.

conclusionsOur series provides the first multicenter experience on EFTR for resection of colorectal SMIC from the United States. Longitudinal data from large scale studies are required to validate our initial experience of EFTR for SMIC.

Indexed as

ColonoscopyColorectal NeoplasmsEndoscopic Mucosal ResectionIntestinal MucosaAgedAged, 80 and overFemaleHumansMaleMiddle AgedNeoplasm InvasivenessRetrospective StudiesTreatment OutcomeUnited StatesEndoscopic full thickness resectionEndoscopic resectionFull thickness resection deviceMalignant polyps

Identifiers

PMID41144225

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.