Evidence map›Paper›PMID 41144124›Full record

ReviewJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2026

Advances in VT ablation for arrhythmogenic cardiomyopathy: evidence, mapping and ablation strategies, and predictive factors.

Mohamed Abdelazeem, Amir Abdelghany, Mohamed Sharief, Ahmed Ammar

Abstract readReview
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In one paragraph

Review in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohamed AbdelazeemUMass Chan-Baystate Medical Centre, Springfield, MA, USA. mohamed.abdelazeem@baystatehealth.org.ORCID http://orcid.org/0000-0002-2663-9772
Amir AbdelghanyCardiology Department, King Abdullah Medical Complex, Jeddah, Saudi Arabia.
Mohamed ShariefMersey and West Lancashire Teaching Hospitals NHS Foundation Trust, Rainhill, UK.
Ahmed AmmarCardiology Department, Worcestershire Acute Hospitals NHS Trust, Worcester, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Catheter ablation of ventricular tachycardia (VT) in arrhythmogenic cardiomyopathy (ACM) is a crucial yet challenging procedure, given the evolving disease definitions, diverse subtypes, genetic variability, complexities in risk stratification, and the intricate substrate distribution characteristic of this condition. Initially described as a right ventricular cardiomyopathy (ARVC), ACM now encompasses left-dominant (ALVC) and biventricular (ABVC) phenotypes, driven by desmosomal (e.g., DSP, PKP2) and non-desmosomal (e.g., FLNC, LMNA) mutations, with fibrosis as the primary arrhythmic substrate. Catheter ablation, particularly combined endocardial-epicardial approaches, reduces VT burden but faces high recurrence rates in younger patients and those with extensive scarring. In this review, we critically assess the role of VT ablation in ACM, current evidence, available techniques for mapping and ablation, outcomes and predictors of success of the ablation procedure in this patient group.

Indexed as

Arrhythmogenic Right Ventricular DysplasiaCatheter AblationTachycardia, VentricularBody Surface Potential MappingEvidence-Based MedicineHumansTreatment OutcomeArrhythmogenic cardiomyopathy (ACM)Arrhythmogenic right ventricular cardiomyopathy (ARVC)Catheter ablation (CA)Sudden cardiac death (SCD)Ventricular tachycardia (VT)

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.