Evidence map›Paper›PMID 41144082›Full record

ArticleRice (New York, N.Y.)2025

OsLEML2 Regulates Rice Thermotolerance Through Auxin and ROS Homeostasis.

Xingzhuo Sun, Yuwei Wang, Yulin Chen, Peng Zhang, Yanting Li, Tongyue Ouyang, Lihua Li, Jianqing Zhu, Xiaomei Jia, Xiaoying Ye and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Rice (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xingzhuo Sun *State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute of Sichuan Agricultural University, Chengdu, 611130, China.
Yuwei Wang *State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute of Sichuan Agricultural University, Chengdu, 611130, China.
Yulin ChenState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute of Sichuan Agricultural University, Chengdu, 611130, China.
Peng ZhangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute of Sichuan Agricultural University, Chengdu, 611130, China.
Yanting LiState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute of Sichuan Agricultural University, Chengdu, 611130, China.
Tongyue OuyangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute of Sichuan Agricultural University, Chengdu, 611130, China.
Lihua LiState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute of Sichuan Agricultural University, Chengdu, 611130, China.
Jianqing ZhuDemonstration Base for International Science & Technology Cooperation of Sichuan Province, Sichuan Agricultural University, 211, Huimin Road, Chengdu, 611130, China.
Xiaomei JiaDemonstration Base for International Science & Technology Cooperation of Sichuan Province, Sichuan Agricultural University, 211, Huimin Road, Chengdu, 611130, China.
Xiaoying YeDemonstration Base for International Science & Technology Cooperation of Sichuan Province, Sichuan Agricultural University, 211, Huimin Road, Chengdu, 611130, China.
Jun ZhuState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute of Sichuan Agricultural University, Chengdu, 611130, China.
Rongjun ChenState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute of Sichuan Agricultural University, Chengdu, 611130, China. 13782@sicau.edu.cn.

Funding

Sichuan Provincial Natural Science Foundation 2024NSFSC0342 and 2025ZNSFSC0159
6 · The paper itself

Abstract

Escalating global warming threatens rice (Oryza sativa L.) growth and yield, making research into thermotolerance mechanisms imperative. OsLEML2, identified as a heat-responsive gene through microarray screening, was investigated in this study. It was found that overexpression of OsLEML2 reduces thermotolerance in transgenic plants. RT-qPCR analysis and physiological parameter measurements revealed that OsLEML2 disrupts reactive oxygen species homeostasis as well as suppresses HSF-HSP signaling. This gene affects the expression of auxin biosynthesis genes and catabolic genes, thereby influencing auxin homeostasis and regulating the heat tolerance of rice. Additionally, OsLEML2 potentially regulates thermotolerance by maintaining cellular auxin homeostasis through facilitating the efflux of excess auxin or its sequestration into the central vacuole, and by modulating pollen viability through the regulation of pollen reactive oxygen species levels. Collectively, our functional characterization has identified OsLEML2 as a negative regulatory factor in heat stress responses, providing a potential genetic target for enhancing thermotolerance in crops via molecular breeding strategies.

Indexed as

Auxin homeostasisHeat stressOsLEML2ROS homeostasis

Identifiers

PMID41144082
PMCPMC12559542

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.