SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
The impact of nutritional intervention on postoperative prognosis in gynecological cancer patients: a systematic review and meta-analysis.
Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Best evidence summary of non-pharmacological interventions for postoperative abdominal distension in gynecological laparoscopic.Frontiers in medicine · 2026Pooled it
- Preoperative Total Iron-Binding Capacity Is a Novel Surrogate Marker of Short- and Long-Term Outcomes After Liver Resection for Hepatocellular Carcinoma.Annals of gastroenterological surgery · 2026Article
- Nutrition literacy and dietary self-management in breast and gynecologic cancer survivorship.Frontiers in public health · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
introductionGynecological cancers present a major global health challenge, with malnutrition recognized as a significant factor worsening prognosis. Extensive surgical procedures and chemotherapy often compromise nutritional status, leading to delayed recovery and poor outcomes. This review aimed to assess the role of nutritional interventions in improving postoperative prognosis among gynecological cancer patients. METHODOLOGY: Following PRISMA guidelines, PubMed, ScienceDirect, and Google Scholar were searched up to August 2025. Eligible randomized trials, cohort, and feasibility studies evaluated nutritional interventions, including early oral feeding, oral supplements, parenteral nutrition, prehabilitation, coffee, and gum chewing. Risk of bias was assessed using Cochrane RoB 2.0 and ROBINS-I. Data were narratively synthesized, with random-effects meta-analysis performed where appropriate. This study has been registered with PROSPERO (CRD420251071481).
resultsA total of 13 studies (randomized and observational) were included. Pooled analyses showed no overall difference in hospital stay between nutritional interventions and standard care (MD -0.56 days; 95% CI -1.34 to 0.22), though subgroup analysis revealed that early oral feeding (EOF), coffee, and gum chewing significantly shortened hospitalization, while total parenteral nutrition (TPN) prolonged it. Nutritional interventions did not significantly reduce postoperative complications overall (OR 0.85; 95% CI 0.55-1.32), but EOF and gum chewing lowered infective and ileus-related morbidity in some studies. Gastrointestinal recovery was consistently accelerated with EOF, coffee, and gum chewing, whereas TPN delayed recovery. Oral nutritional supplements (ONS) improved nutritional indices, and prehabilitation shortened the time to chemotherapy. Survival outcomes were rarely reported, with malnutrition predicting poor prognosis. Overall, interventions were safe and well-tolerated.
conclusionNutritional interventions, particularly EOF, coffee, gum chewing, and ONS, enhance recovery and nutritional status in gynecologic oncology, whereas TPN should be reserved for selected malnourished patients.
Indexed as
Identifiers
41144033What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.