Evidence map›Paper›PMID 41144026›Full record

ArticleLasers in medical science2025

Effect of Er:YAG Laser with or without fluoride on the prevention and progression of erosive tooth wear in primary enamel: an in vitro study.

Camila Cardoso Cabral, Mirian Lumi Yoshida, Laís Maria Cardoso Cabral, Denise Maria Zezell, Ana Cecilia Correa Aranha

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Article in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Camila Cardoso CabralDepartament of Restorative Dentistry, School of Dentistry, University of São Paulo, São Paulo, Brazil.
Mirian Lumi YoshidaDepartament of Restorative Dentistry, School of Dentistry, University of São Paulo, São Paulo, Brazil.
Laís Maria Cardoso CabralDepartment of Pharmacology, Institute of Biomedical Sciences (ICB), University of São Paulo, São Paulo, Brazil.
Denise Maria ZezellNuclear and Energy Research Institute IPEN-CNEN, Center for Lasers and Applications CLA (Primary), University of São Paulo, São Paulo, Brazil.
Ana Cecilia Correa AranhaDepartament of Restorative Dentistry, School of Dentistry, University of São Paulo, São Paulo, Brazil. acca@usp.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to assess the effect of the Er:YAG laser, either alone or in combination with topical fluoride application, on the prevention and progression of erosive tooth wear in primary enamel. A total of 120 extracted human primary molars were flattened, polished, and divided based on substrate condition: sound or previously eroded with citric acid. The specimens were allocated into 12 experimental groups and received one of the following treatments: no treatment (control), topical application of acidulated phosphate fluoride (APF 1.23%), irradiation with Er: YAG laser using two different protocols (0.20 W and 0.40 W), or combinations of laser followed by fluoride application. All samples were then subjected to a five-day erosive remineralization cycling protocol, involving repeated acid exposure (pH 2.6) and immersion in artificial saliva. Enamel surface loss was assessed by optical profilometry, and morphological changes were evaluated by environmental scanning electron microscopy. The findings demonstrated that all interventions tested, including laser irradiation, fluoride application, and their combinations, were effective in reducing enamel loss when compared to untreated controls. However, no statistically significant differences were found between the various treatment protocols. The results suggest a promising protective effect of Er: YAG laser and fluoride treatments for preventing and controlling the progression of erosive tooth wear in primary enamel, highlighting the need for further research to confirm their efficacy.

Indexed as

Dental EnamelFluoridesFluorides, TopicalLasers, Solid-StateTooth ErosionAcidulated Phosphate FluorideHumansIn Vitro TechniquesMicroscopy, Electron, ScanningTooth, DeciduousTooth RemineralizationAcidulated Phosphate FluorideFluoridesFluorides, TopicalEnamelErosionEr:YAG laserFluorideLaserPreventionTooth wear

Identifiers

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Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.