Evidence map›Paper›PMID 41143865›Full record

ArticleJournal of neurophysiology2025

Role of BK channels and Kv4.2 channels in the electrophysiological properties of Merkel cells in rat whisker hair follicles.

Akihiro Yamada, Jianguo Gu

Abstract read
In one paragraph

Article in Journal of neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Akihiro YamadaDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Jianguo GuDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States.

Funding

Mechanisms of Nociception in the Trigeminal SystemR01DE018661 · NIDCR · UNIVERSITY OF FLORIDA · PI JIANGUO GU · 2008 to 2026
$6.9M
Cellular and Ion Channel Mechanisms Underlying the Sense of Light Touch in MammalsR01DE023090 · NIDCR · UNIVERSITY OF CINCINNATI · PI JIANGUO GU · 2013 to 2026
$6.1M
HHS | NIH | National Institute of Dental and Craniofacial Research (NIDR) DE018661HHS | NIH | National Institute of Dental and Craniofacial Research (NIDR) DE023090NIDCR NIH HHS R01 DE018661NIDCR NIH HHS R01 DE023090
6 · The paper itself

Abstract

Merkel cells are excitable cells in the skin and the whisker hair follicles that detect tactile stimuli, leading to the sense of touch. Previous studies have identified Piezo2 channels as mechanical transducers in Merkel cells, and their activation excites Merkel cells to fire Ca

Indexed as

Hair FollicleLarge-Conductance Calcium-Activated Potassium ChannelsMerkel CellsShal Potassium ChannelsVibrissaeAction PotentialsAnimalsMaleMembrane PotentialsPatch-Clamp TechniquesPeptidesPotassium Channel BlockersRatsRats, Sprague-DawleyTetraethylammoniumiberiotoxinLarge-Conductance Calcium-Activated Potassium ChannelsPeptidesPotassium Channel BlockersShal Potassium ChannelsTetraethylammoniumBK channelKv4.2 channelmechanoreceptorsMerkel cellPiezo2

Identifiers

PMID41143865
PMCPMC12584268

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.