Evidence map›Paper›PMID 41143048›Full record

SynthesisFrontiers in psychology2025

Multilevel meta-analysis of the effect of exercise intervention on inhibitory control in children with ASD.

Xiangqin Song, Yaoqi Hou, Zonghan Lei, Shenning Zhou

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiangqin SongCollege of Physical Education and Sports, Beijing Normal University, Beijing, China.
Yaoqi HouCollege of Physical Education and Sports, Beijing Normal University, Beijing, China.
Zonghan LeiUniversity of New South Wales, Sydney, NSW, Australia.
Shenning ZhouCollege of Physical Education and Sports, Beijing Normal University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Inhibitory control deficits represent a core cognitive challenge for children with Autism Spectrum Disorder (ASD), impacting behavioral regulation, social interaction, and adaptive functioning. Exercise interventions have emerged as promising non-pharmacological approaches for cognitive enhancement, yet their specific effects on inhibitory control in the ASD population remain unclear. This study aimed to systematically evaluate the efficacy of exercise interventions on inhibitory control in children and adolescents with ASD. Methods: This systematic review and multilevel meta-analysis followed PRISMA guidelines and was prospectively registered (PROSPERO: CRD420251039964). We systematically searched five electronic databases (PubMed, Web of Science, Embase, Cochrane Library, and CNKI) from inception to December 2023. Randomized and quasi-randomized controlled trials evaluating exercise interventions for inhibitory control in ASD populations were included. Study quality was assessed using the Cochrane Risk of Bias Tool (ROB2). Effect sizes were calculated as standardized mean differences (SMDs) and synthesized using a three-level meta-analytic approach to account for dependency among effect sizes. Subgroup analyses and meta-regression explored potential moderators of intervention efficacy. Results: Ten studies comprising 466 participants (229 in intervention groups) met inclusion criteria. Exercise interventions demonstrated significant positive effects on inhibitory control in children with ASD (SMD = 0.66, 95% CI [0.44, 0.88]). Structured exercise interventions showed differential efficacy, with Mini Basketball (SMD = 0.95), Martial Arts (SMD = 0.90), and Bicycle Learning (SMD = 0.86) yielding the largest effects. Meta-regression identified total training duration as a significant positive predictor of intervention efficacy ( Conclusion: This meta-analysis provides robust evidence supporting exercise interventions, particularly structured activities combining physical and cognitive demands, for improving inhibitory control in children with ASD. The findings suggest important clinical implications for intervention design, highlighting the value of adequate intervention duration and early implementation. Future research should address methodological limitations through high-quality trials with standardized protocols and extended follow-up periods. Systamatic review: CRD420251039964.

Indexed as

autism spectrum disordercognitive enhancementexecutive functionmultilevel meta-analysisneurodevelopmental disordersphysical activity

Identifiers

PMID41143048
PMCPMC12546240

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.