ArticleiScience2025
Analysis of neuronal activity impairment in iPSC-derived neurons from idiopathic autism patients.
Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Pathological Priming and Developmental Heterochrony as Organizing Concepts in Human iPSC Models of Autism Spectrum Disorder.Molecular neurobiology · 2026Review
- Aberrant neuronal differentiation and splicing defects in Congenital Myotonic Dystrophy (DM1) iPSC models.bioRxiv : the preprint server for biology · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
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Abstract
Understanding the molecular mechanisms underlying autism spectrum disorder (ASD) is crucial to develop effective interventions. Here, we utilized induced pluripotent stem cells differentiated into neurons (iPSC-Ns) from idiopathic ASD and control individuals (CTRL) to investigate the molecular basis of ASD. ASD-iPSC-Ns exhibited functional alterations displaying less calcium transients compared to CTRL. Different expression levels of microRNAs involved in neurogenesis and neuronal functioning might underlie these differences. ASD-iPSC-N neuronal networks showed impaired synaptic neurotransmission and connectivity (decreased [Ca
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