Evidence map›Paper›PMID 41142995›Full record

ArticleiScience2025

Detection of dedifferentiated stem cells in the

Muhammed Burak Bener, Stella M DiPippo, Boris M Slepchenko, Mayu Inaba

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Stem cell competition.Current topics in developmental biology · 2026
    Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Muhammed Burak BenerDepartment of Cell Biology, University of Connecticut Health, Farmington, CT 06030, USA.
Stella M DiPippoDepartment of Cell Biology, University of Connecticut Health, Farmington, CT 06030, USA.
Boris M SlepchenkoDepartment of Cell Biology, University of Connecticut Health, Farmington, CT 06030, USA.
Mayu InabaDepartment of Cell Biology, University of Connecticut Health, Farmington, CT 06030, USA.

Funding

Mechanistic Modeling of Cellular SystemsR24GM137787 · NIGMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI Pedro Mendes, Ion I. Moraru · 2020 to 2026
$8.9M
Nanotube-mediated regulation of niche-stem cell signalingR35GM128678 · NIGMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI Mayu Inaba-Oguro · 2018 to 2026
$3.3M
NIGMS NIH HHS R24 GM137787NIGMS NIH HHS R35 GM128678
6 · The paper itself

Abstract

Dedifferentiation is the process by which partially or terminally differentiated cells revert to a stem cell state, a conserved mechanism that supports stem cell maintenance across various systems. In the

Indexed as

Developmental geneticsExperimental models in systems biologyStem cells research

Identifiers

PMID41142995
PMCPMC12547877

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.