Evidence map›Paper›PMID 41142942›Full record

ArticleOpen life sciences2025

The TNFR-RIPK1/RIPK3 signalling pathway mediates the effect of lanthanum on necroptosis of nerve cells.

Bihui Jin, Zhe Ding, Yujiao Sun, Shujuan Gao, Xinyu Sui, Mengping Ding, Xinyi Qu, Linlin Zheng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open life sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bihui JinInstitute of Molecular Medicine, School of Medicine, Liaodong University, Dandong, 118003, Liaoning, People's Republic of China.
Zhe DingInstitute of Molecular Medicine, School of Medicine, Liaodong University, Dandong, 118003, Liaoning, People's Republic of China.
Yujiao SunInstitute of Molecular Medicine, School of Medicine, Liaodong University, Dandong, 118003, Liaoning, People's Republic of China.
Shujuan GaoInstitute of Molecular Medicine, School of Medicine, Liaodong University, Dandong, 118003, Liaoning, People's Republic of China.
Xinyu SuiInstitute of Molecular Medicine, School of Medicine, Liaodong University, Dandong, 118003, Liaoning, People's Republic of China.
Mengping DingInstitute of Molecular Medicine, School of Medicine, Liaodong University, Dandong, 118003, Liaoning, People's Republic of China.
Xinyi QuInstitute of Molecular Medicine, School of Medicine, Liaodong University, Dandong, 118003, Liaoning, People's Republic of China.
Linlin ZhengInstitute of Molecular Medicine, School of Medicine, Liaodong University, Dandong, 118003, Liaoning, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lanthanum (La) accumulates resulted in detrimental alterations in the morphology and structure of hippocampal neurons, but the specific mechanism remains unclear. At 49 days after the birth of LaCl

Indexed as

Lalearning and memorymixed lineage kinase domain-like proteinnecroptosisreceptor-interacting protein kinasestumour necrosis factor receptors

Identifiers

PMID41142942
PMCPMC12552855

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.