Evidence map›Paper›PMID 41142906›Full record

ReviewPatterns (New York, N.Y.)2025

Large language models for drug discovery and development.

Yizhen Zheng, Huan Yee Koh, Jiaxin Ju, Madeleine Yang, Lauren T May, Geoffrey I Webb, Li Li, Shirui Pan, George Church

Abstract readReview
In one paragraph

Review in Patterns (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  13. Drug response in the era of precision medicine: A methodological review.Computational and structural biotechnology journal · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yizhen ZhengDepartment of Data Science and AI, Monash University, Melbourne, VIC, Australia.
Huan Yee KohDepartment of Data Science and AI, Monash University, Melbourne, VIC, Australia.
Jiaxin JuSchool of Information and Communication Technology, Griffith University, Gold Coast, QLD, Australia.
Madeleine YangDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Lauren T MayDrug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, VIC, Australia.
Geoffrey I WebbDepartment of Data Science and AI, Monash University, Melbourne, VIC, Australia.
Li LiDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Shirui PanSchool of Information and Communication Technology, Griffith University, Gold Coast, QLD, Australia.
George ChurchDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The integration of large language models (LLMs) into the drug discovery and development field marks a significant paradigm shift, offering novel methodologies for understanding disease mechanisms, facilitating

Indexed as

drug developmentdrug discoverylarge language models

Identifiers

PMID41142906
PMCPMC12546459

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.