Evidence map›Paper›PMID 41142855›Full record

ArticleRadiology case reports2026

Secondary bilateral adrenal Burkitt lymphoma with hepatic and renal involvement in a 17-year-old patient: A rare case report and literature review.

Nora Elmassoudi, Yasmine Aznague, Mohamed Ayez, Said Adnor, Mohamed Laghdaf Maouelainin, Abir Saalaoui, Mohamed Tbouda, Hassan Doulhousne, Soukaina Wakrim, Abdennasser Elkharras

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In one paragraph

Article in Radiology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Nora ElmassoudiRadiology Department, Universal Hospital of Souss Massa, Agadir, Morocco.
Yasmine AznagueRadiology Department, Universal Hospital of Souss Massa, Agadir, Morocco.
Mohamed AyezRadiology Department, Universal Hospital of Souss Massa, Agadir, Morocco.
Said AdnorRadiology Department, Universal Hospital of Souss Massa, Agadir, Morocco.
Mohamed Laghdaf MaouelaininRadiology Department, Oued Eddahab Military Hospital, Agadir, Morocco.
Abir SaalaouiRadiology Department, Universal Hospital of Souss Massa, Agadir, Morocco.
Mohamed TboudaFaculty of Medicine and Pharmacy of Agadir, Ibn Zohr University, Agadir, Morocco.
Hassan DoulhousneFaculty of Medicine and Pharmacy of Agadir, Ibn Zohr University, Agadir, Morocco.
Soukaina WakrimRadiology Department, Universal Hospital of Souss Massa, Agadir, Morocco.
Abdennasser ElkharrasFaculty of Medicine and Pharmacy of Agadir, Ibn Zohr University, Agadir, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Secondary adrenal involvement by lymphoma is rare in adolescents, and Burkitt lymphoma in this location is exceptional. We report a 17-year-old male with no prior medical history who presented with 3 months of persistent bilateral flank pain and significant unexplained weight loss. Contrast-enhanced computed tomography (CT) demonstrated large bilateral adrenal masses with central necrosis and direct contiguous extension into the adjacent liver and kidneys, while adrenal function remained preserved. No residual adrenal parenchyma was identifiable. CT-guided biopsy and immunohistochemistry confirmed Burkitt lymphoma with diffuse CD20 expression and a Ki-67 proliferation index approaching 100%. The patient received the pediatric-adapted Lymphomes Malins B (LMB) chemotherapy protocol. This case highlights the diagnostic challenges and aggressive behavior of adrenal Burkitt lymphoma in young patients and emphasizes the importance of early recognition, biopsy, and prompt initiation of intensive therapy.

Indexed as

AdolescentAdrenal gland neoplasmsBurkitt lymphomaKidney neoplasms/secondaryLiver neoplasms/secondaryLymphoma, Non-Hodgkin

Identifiers

PMID41142855
PMCPMC12550709

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