Evidence map›Paper›PMID 41142847›Full record

ArticleThe journal of liquid biopsy2025

Crossing barriers with CSF-based sequencing for leptomeningeal disease in EGFR mutant NSCLC.

Bhuvan Chugh, Richa Dave, Aarthi Ramesh, Ganesh Khutale, Kanchan Hariramani, Saloni Andhari, Alain D'Souza, Sandhya Iyer, Madhura Basavalingegowda, Sumit Halder and 5 more

Abstract read
In one paragraph

Article in The journal of liquid biopsy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Bhuvan ChughMax Institute of Cancer Care, Max Super Speciality Hospital, Saket, New Delhi, Delhi, 110017, India.
Richa Dave1Cell.Ai, Wakad, Pune, 411057, India.
Aarthi Ramesh1Cell.Ai, Wakad, Pune, 411057, India.
Ganesh Khutale1Cell.Ai, Wakad, Pune, 411057, India.
Kanchan Hariramani1Cell.Ai, Wakad, Pune, 411057, India.
Saloni Andhari1Cell.Ai, Wakad, Pune, 411057, India.
Alain D'Souza1Cell.Ai, Wakad, Pune, 411057, India.
Sandhya Iyer1Cell.Ai, Wakad, Pune, 411057, India.
Madhura Basavalingegowda1Cell.Ai, Wakad, Pune, 411057, India.
Sumit Halder1Cell.Ai, Wakad, Pune, 411057, India.
Hrishita Kothavade1Cell.Ai, Wakad, Pune, 411057, India.
Aravindan Vasudevan1Cell.Ai, Wakad, Pune, 411057, India.
Atul Bharde1Cell.Ai, Wakad, Pune, 411057, India.
Jayant Khandare1Cell.Ai, Wakad, Pune, 411057, India.
Gowhar Shafi1Cell.Ai, Wakad, Pune, 411057, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report highlights the critical role of cerebrospinal fluid (CSF)-based sequencing in precision oncology for a 64-year-old female with metastatic

Indexed as

Cerebrospinal fluid (CSF)-based next-generation sequencing (NGS)Circulating tumor DNA (ctDNA)EGFR and ERBB2 alterationsLeptomeningeal metastasisLiquid biopsyNon-small cell lung cancer (NSCLC)

Identifiers

PMID41142847
PMCPMC12550170

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.