Evidence map›Paper›PMID 41142717›Full record

ArticleAsia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology2025

The incidence of arthrogenic muscle inhibition in acute knee injuries: a prospective cohort study in a tertiary acute knee unit.

M J Kennedy, C S Leung, T C F Soh, H Sitton-Kent, H J Thomson, O Hill, T Nunn, O Bailey, G P Hopper, R Bhattacharyya

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Article in Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

M J KennedySchool of Medicine, University of St. Andrews, St. Andrews, Fife, KY16 9TF, UK.
C S LeungSchool of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, G12 8QQ, UK.
T C F SohLanarkshire Acute Knee Service, NHS Lanarkshire University Hospitals, UK.
H Sitton-KentSchool of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, G12 8QQ, UK.
H J ThomsonSchool of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, G12 8QQ, UK.
O HillSchool of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, G12 8QQ, UK.
T NunnRoyal Alexandra Hospital, Corsebar Rd, Paisley, PA2 9PN, UK.
O BaileyLanarkshire Acute Knee Service, NHS Lanarkshire University Hospitals, UK.
G P HopperLanarkshire Acute Knee Service, NHS Lanarkshire University Hospitals, UK.
R BhattacharyyaLanarkshire Acute Knee Service, NHS Lanarkshire University Hospitals, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Arthrogenic Muscle Inhibition (AMI) is not well recognised and is therefore underdiagnosed. Improved understanding of AMI would allow improved patient treatment pathways and rehabilitation after acute knee injuries. The primary aim of this study was to evaluate the incidence of AMI in acute knee injuries. The secondary aim was to evaluate correlation between AMI and type of underlying knee injury. Methods: This was a prospective cohort study. All patients reviewed by the acute knee service in a tertiary referral centre between January 01, 2023 and April 30, 2023 were included (n = 97). The patients were diagnosed with AMI by a fellowship trained orthopaedic consultant knee surgeon. The incidence was evaluated with descriptive statistics and logistic regression analysis performed to ascertain association of AMI with the underlying acute knee injury diagnosis. Results: Of the 97 patients reviewed, 12 were excluded due to a mechanical block to extension on MRI imaging. Twenty-seven (31.8 %) of the 85 eligible patients were diagnosed with AMI. Nine of the twenty-seven patients (52 %) presenting with AMI had resolution of symptoms at the index clinic appointment with directed physical therapy. Patients with AMI were 6 times (OR 6.3, 95 % CI 1.48) more likely to have a diagnosis of patellofemoral (PFJ) dislocation (p = 0.013) than those with bone bruising or minor sprain. Other associations of AMI which did not reach statistical significance were meniscal tear (OR 4.2, 95 % CI 0.4) and ACL rupture (OR 3.5, 95 % CI 0.72). Conclusions: AMI is common in acute knee injuries, affecting nearly a third of all patients reviewed. Patients with AMI were more likely to have an underlying diagnosis of PFJ dislocation than any other acute knee injury diagnosis, and was the only statistically significant association. Correct diagnosis and instituting immediate treatment can resolve >50 % cases at the index clinic appointment. Treatment workflows incorporating early review and management could result in improved patient outcome and expedited recovery from AMI.

Indexed as

ACL ruptureAcute knee injuryAMIArthrogenic muscle inhibitionRehabilitation

Identifiers

PMID41142717
PMCPMC12549524

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.