ArticleArchives of medical sciences. Atherosclerotic diseases2025
Trends in mortality from acute myocardial infarction among the obese population in the United States from 1999 to 2020: insights from CDC WONDER.
Article in Archives of medical sciences. Atherosclerotic diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Acute myocardial infarction (AMI) remains a leading cause of death globally, with obesity identified as a significant risk factor for increased incidence and poorer post-event outcomes. Understanding trends in AMI mortality among obese populations is crucial for informing public health strategies, especially in light of rising obesity rates. Material and methods: This retrospective study analyzed data from the CDC WONDER database to examine AMI-related mortality among obese individuals (ICD-10 codes I21 for AMI and E66 for obesity) from 1999 to 2020. Mortality rates were assessed using crude mortality rates (CMR) and age-adjusted mortality rates (AAMR) per 100,000, stratified by year, gender, race/ethnicity, state, and urban-rural status. Average annual percent change (AAPC) was calculated to identify trends over the study period. Results: From 1999 to 2020, there were 39,793 obesity-related AMI deaths. The AAPC for the entire period was 1.75 (95% CI: 1.06 to 2.45, Conclusions: The study highlights an upward trend in AMI-related mortality among the obese population in the U.S. from 1999 to 2020. Targeted public health interventions are needed to address these trends, particularly in high-risk populations.
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