ArticleJournal of multidisciplinary healthcare2025
Rheumatoid Arthritis and Fibromyalgia Syndrome: A Bibliometric and Bioinformatics Perspective on Comorbidity Research.
Article in Journal of multidisciplinary healthcare, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Research hotspots, context, and future directions of ulcerative colitis comorbid with depression from 2006 to 2025: a bibliometric and visualization analysis.Frontiers in medicine · 2026Pooled it
- Research on adaptive collaborative dispatch optimization algorithms for drones in distribution networks.Scientific reports · 2026Article
- Identification and Experimental Validation of Key Biomarkers for Rheumatoid Arthritis Based on Bioinformatics Analysis and Machine Learning.Journal of inflammation research · 2026Article
- Global trends and hotspots of artificial intelligence in pain management: A bibliometric analysis.Digital healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Rheumatoid arthritis (RA) and fibromyalgia syndrome (FMS) are two common chronic pain disorders which complicate diagnosis and treatment. However, the pathological mechanisms, epidemiological characteristics, and research trends in comorbidities have not yet been systematically reviewed. Methods: Literature related to RA and FMS published between January 2015 and December 2024 was retrieved from the Web of Science (WOS) database. VOSviewer, CiteSpace, Scimago Graphica, and Excel were used to conduct co-occurrence and clustering analyses of countries, institutions, authors, journals, and keywords to evaluate research dynamics and knowledge structures. GeneCards was used to identify shared gene targets between RA and FMS, whereas Protein-Protein Interaction (PPI) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed to explore potential comorbidity mechanisms. Results: In total, 760 articles were included in the study, with annual publication counts showing periodic fluctuations. The United States consistently ranked first in publication output and formed a highly influential collaborative network. Among the institutions, the Conclusion: Current research on RA-FMS comorbidity lacks depth and mechanistic insight. Future studies should explore neuroimmune regulation, central sensitization, and inflammation-pain pathways through interdisciplinary collaboration across rheumatology, neuroscience, pain medicine, and bioinformatics to establish a unified comorbidity framework.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.