ArticleFrontiers in veterinary science2025
Comparative genomics of Shiga toxin-producing
Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Comparative pangenomics of Pasteurella multocida uncovers adhesins specific to capsular serogroup B strains associated with bovine host tropism.BMC microbiology · 2026Article
- AnMicrobiology spectrum · 2026Article
- Distinct Tissue Localization and Transcriptional Profiles of Shiga Toxin-ProducingInternational journal of microbiology · 2026Article
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Authors and funding
16 authors.
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Abstract
Introduction: Shiga toxin-producing Methods: A total of 948 fecal samples from Chilean cattle were screened, yielding 71 confirmed STEC isolates, which were analyzed alongside 546 publicly available genomes to compare host-specific adhesion patterns. The adhesiome was examined based on gene presence/absence patterns, followed by a genome-wide association study (GWAS) and variant effect analysis to identify host-specific adhesion genes and their functional implications. Results: Adhesin gene analysis revealed distinct adhesion strategies between hosts. Several genes, including Discussion: Our findings provide new insights into STEC host adaptation and highlight potential targets to reduce zoonotic transmission and improve pre-harvest food safety strategies. Future research should focus on functional validation of host-specific adhesin variants and their potential as preventive strategies.
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