Evidence map›Paper›PMID 41142516›Full record

ArticleJournal of exercise science and fitness2025

Effects of two different doses of HIFT on physical function, cognitive performance, and quality of life in older adults with mild cognitive impairment: A randomized controlled trial.

Diego Fernando Afanador-Restrepo, Yulieth Rivas-Campo, Carlos Mario Basto-Cardona, David Alejandro Gonzalez-Bustamante, Agustin Aibar-Almazan, Yolanda Castellote-Caballero, Fidel Hita-Contreras, Eduardo Guzmán-Muñoz, Yeny Concha-Cisternas

Abstract read
In one paragraph

Article in Journal of exercise science and fitness, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Diego Fernando Afanador-RestrepoZIPATEFI Research Group, Faculty of Health Sciences and Sports, University Foundation of the Área Andina, 660001, Colombia.
Yulieth Rivas-CampoFaculty of Human and Social Sciences, University of San Buenaventura, 760016, Colombia.
Carlos Mario Basto-CardonaGIP Pedagogy Research Group, Faculty of Distance and Virtual Education, Antonio José Camacho University Institution, 760016, Colombia.
David Alejandro Gonzalez-BustamanteGRINDER Research Group, Physical Education and Sport Departament, University of Valley, 760042, Colombia.
Agustin Aibar-AlmazanDepartment of Health Sciences, Faculty of Health Sciences, University of Jaén, 23071, Spain.
Yolanda Castellote-CaballeroDepartment of Health Sciences, Faculty of Health Sciences, University of Jaén, 23071, Spain.
Fidel Hita-ContrerasDepartment of Health Sciences, Faculty of Health Sciences, University of Jaén, 23071, Spain.
Eduardo Guzmán-MuñozSchool of Kinesiology, Faculty of Health, Universidad Santo Tomás, 360000, Chile.
Yeny Concha-CisternasVice-Rectory for Research and Innovation, Universidad Arturo Prat, 1100000, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Objective: Mild cognitive impairment (MCI) compromises physical and mental function in older adults and increases the risk of dementia. High-Intensity Functional Training (HIFT) is a promising intervention, but the optimal dose-response for improving cognitive and physical outcomes in this population remains unclear. Methods: A randomized controlled trial was conducted with 224 older adults (≥65 years) allocated to three groups: high-dose HIFT (4 sessions of 60 min/week), low-dose HIFT (2 sessions of 45 min/week), and control (non-exercise activities). The intervention lasted 12 weeks. Primary outcomes included cognitive function (MAAS, MoCA, TMT A/B, VFAT, DSST), physical fitness (Senior Fitness Test, Tinetti), and quality of life (SF-36, PSQI). A repeated-measures ANOVA was used to examine the time × group interaction. Results: Significant time × group interactions were observed for MAAS (F = 20.50; p < 0.001; η Conclusion: Both high- and low-dose HIFT programs improved cognitive, physical, and quality-of-life outcomes in older adults with MCI. The low-dose intervention achieved similar effects to the high-dose protocol, offering a time-efficient and scalable approach for implementation in clinical and community settings.

Indexed as

AgingCognitive dysfunctionExercise therapyHigh-intensity interval trainingMild cognitive impairmentQuality of life

Identifiers

PMID41142516
PMCPMC12550297

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.