ArticleWomen's health reports (New Rochelle, N.Y.)2025
Management of Endometrial Intraepithelial Neoplasia: A Retrospective Review of Practice Patterns at a Single Military Treatment Facility and Civilian Partner Hospital.
Article in Women's health reports (New Rochelle, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Endometrial intraepithelial neoplasia (EIN) is a known precursor to endometrial endometrioid carcinoma, with a 40% risk of concurrent endometrial cancer at the time of hysterectomy. Many benign gynecologists (GYN) refer to gynecologic oncologists (GYO) for this risk of malignancy. This retrospective cohort study describes the pathological outcomes of patients with EIN who underwent hysterectomy at a single military treatment facility (MTF) and a civilian partner hospital. Methods: A retrospective chart review was performed for patients with a diagnosis of EIN at a single MTF and civilian hospital from 1/1/2021 to 10/30/2023. Preoperative risk factors for malignancy of cases performed by GYN and GYO were compared. Results: A total of 58 patients with EIN were included (8 from the MTF, 50 from the civilian partner hospital). Of these, 48 (82.8%) patients were referred to GYO for hysterectomy. Thirty-three (56.9%) patients were upstaged to endometrial cancer, with 28 (84.5%) Stage IA, 3 (9.1%) Stage IB, and 2 (3.4%) Stage III. Of the 48 patients in the GYO cohort, 36 patients underwent nodal sampling with only one lymph node positive for metastasis. No patients required secondary staging procedures. No significant preoperative risk factors were identified for advanced cancer. Conclusions: Our data supports prior literature suggesting that the likelihood of nodal involvement and advanced metastatic disease in patients with EIN is low. Current guidelines allow flexibility in the management of EIN by either GYN or GYO. Additional research into and application of preoperative risk algorithms may help identify patient risk for advanced malignancy and accurately guide low-risk patients towards management by GYN and high-risk patients by GYO.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.