Evidence map›Paper›PMID 41142458›Full record

ReviewInternational journal of nanomedicine2025

Emerging Role of Plant-Derived Nanostructures in Nanomedicine.

Huijie Xing, Guichan Li, Chunli Qi, Ming Zhang, Ning Ding, Xingwang Zhang

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Emerging Nanoplatforms are Effective Against Tumor Hypoxia.International journal of nanomedicine · 2026
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Huijie Xing *Institute of Laboratory Animals, Jinan University, Guangzhou, 510632, People's Republic of China.
Guichan Li *Department of Pharmaceutics, College of Pharmacy, Jinan University, Guangzhou, 511443, People's Republic of China.
Chunli QiInstitute of Laboratory Animals, Jinan University, Guangzhou, 510632, People's Republic of China.
Ming ZhangGuangzhou Baiyun Airport Customs, Guangzhou Customs District, Guangzhou, 510623, People's Republic of China.
Ning DingInstitute of Animal Quarantine, Guangzhou Customs Technology Center, Guangzhou, 510623, People's Republic of China.
Xingwang ZhangDepartment of Pharmaceutics, College of Pharmacy, Jinan University, Guangzhou, 511443, People's Republic of China.ORCID 0000-0002-8824-3917

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant-derived nanostructures (PDNSs) represent a promising class of natural nanomedicines that integrate therapeutic and drug delivery functions. These self-assembled nanosystems, including nanoparticles, nanovesicles, exosomes, and nanofibers, leverage bioactive phytoconstituents to overcome limitations of synthetic biomaterials, such as immunogenicity and suboptimal targeting. PDNSs exhibit unique advantages like high biocompatibility, autonomous formation, and multi-modal functionality. This review examines their structural classification, fabrication methods and characterization techniques. PDNSs, synergistically combining inherent biological activities with engineered delivery properties, are revolutionizing conventional drug delivery systems and therapeutic approaches. Their applications expand into a remarkable spectrum of medical fields, demonstrating outstanding efficacy in oncology, inflammatory disorders, infectious diseases, and tissue engineering. Furthermore, PDNSs exhibit transformative potential in addressing complex neurological and metabolic conditions. Their eco-friendly production, low toxicity, and ability to penetrate biological barriers (eg, the absorption barrier and the blood-brain barrier) establish them as the next frontier in therapeutic development. This review critically evaluates the immense potential of PDNSs to bridge natural medicine and precision nanomedicine, offering translational insights for future applications.

Indexed as

NanomedicineNanostructuresPlantsAnimalsDrug Delivery SystemsHumansTissue Engineeringdrug delivery and therapyexosomesnanomedicinenanoparticlesnanovesiclesphytomedicineplant-derived nanostructures

Identifiers

PMID41142458
PMCPMC12553393

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.