Evidence map›Paper›PMID 41142446›Full record

RevieweNeurologicalSci2025

Rehabilitation for functional enhancement of myasthenia gravis: A systematic review and meta-analysis.

Wen Xiangxiang, Shen Mengjiao, Jia Shoumei, Yu Kaitao, Xu Yafang, Jia Jie

Abstract readReview
In one paragraph

Review in eNeurologicalSci, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wen XiangxiangDepartment of Rehabilitation Medicine, Huashan Hospital, Fudan University, 12 Urumqi Road (M), Shanghai 200040, China.
Shen MengjiaoFudan University, 220 Handan Road, Shanghai 200433, China.
Jia ShoumeiSchool of Nursing, Fudan University, 305 Fenglin Road, Shanghai 200032, China.
Yu KaitaoDepartment of Rehabilitation Medicine, Huashan Hospital, Fudan University, 12 Urumqi Road (M), Shanghai 200040, China.
Xu YafangDepartment of Rehabilitation Medicine, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou 350212, China.
Jia JieDepartment of Rehabilitation Medicine, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou 350212, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myasthenia gravis (MG) is a rare neuromuscular disorder that causes muscle weakness and fatigue. This review evaluated the current evidence on the efficacy, tolerance and adherence of rehabilitative interventions. Based on the PRISMA guidelines, 445 articles were identified from major scientific databases. After applying the inclusion and exclusion criteria, 6 studies were included in the final analysis. Two primary rehabilitative strategies - physical and respiratory training - were identified. The results of the systematic review and meta-analysis showed that both interventions improved functional capacity and enhanced the quality of life, with good tolerance and high adherence. This review summarizes the effects of rehabilitative interventions on improving 6-min walk distance (6MWD), quality of life (MG-QOL15), and respiratory function (FEV1 and FVC) in MG patients. One study was rated as high quality (OCEBM level 1b), and five as moderate quality (OCEBM level 2b). Five findings were established and rated as Grade B, according to the OCEBM recommendations. This review demonstrated the potential of structured rehabilitation programs to improve functioning and quality of life in patients with MG, while highlighting the need for further research to optimize and standardize these interventions.

Indexed as

Muscle weaknessMyasthenia gravisNeuromuscular junctionPhysical trainingRehabilitative interventionsRespiratory training

Identifiers

PMID41142446
PMCPMC12547834

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.