Berlin Heart bridge to transplantation in an 18-month-old with septicaemia and thrombocytopenia: a case report and literature review.

Ashmit Bhardwaj, Rishabh Suvarna, Deepa Sarkar, Reetesh Gupta, Bhaba Nanda Das, Jothi Muthu, Mukesh Goel

Abstract readCase Reports

In one paragraph

Article in Indian journal of thoracic and cardiovascular surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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5 · Who and what money

Authors and funding

7 authors.

Ashmit Bhardwaj *School of Medicine, University of Leeds, Worsley Building, Woodhouse, Leeds, LS2 9 JT UK.ORCID 0009-0002-8334-154X

Rishabh Suvarna *School of Medicine, University of Leeds, Worsley Building, Woodhouse, Leeds, LS2 9 JT UK.ORCID 0009-0001-7011-2863

Deepa SarkarDepartment of Cardiac Anaesthesia, Indraprastha Apollo Hospital, New Delhi, Delhi 110076 India.

Reetesh GuptaDepartment of Paediatric Cardiac Intensive Care, Indraprastha Apollo Hospital, New Delhi, Delhi 110076 India.

Bhaba Nanda DasDepartment of Cardiac Surgery, Indraprastha Apollo Hospital, New Delhi, Delhi 110076 India.

Jothi MuthuDepartment of Cardiac Surgery, Indraprastha Apollo Hospital, New Delhi, Delhi 110076 India.

Mukesh GoelDepartment of Cardiac Surgery, Indraprastha Apollo Hospital, New Delhi, Delhi 110076 India.ORCID 0009-0007-0436-0475

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dilated cardiomyopathy (DCMP), a non-ischaemic heart disease involving ventricular enlargement, is the second most common cause of heart failure, with a prevalence of 1:2500. Few studies document the use of paediatric ventricular assist devices (VADs) such as the Berlin Heart EXCOR (BHE) device in those with sepsis. We report an 18-month-old patient, diagnosed with DCMP-induced refractory heart failure, causing septicaemia and thrombocytopenia. Despite this, BHE implantation was used as a last resort bridge to heart transplantation. Our case highlights the importance of carefully managing BHE in high-risk, compassionate-use patients, challenging existing guidelines and encouraging individualised assessments in VAD application.

Indexed as

Berlin Heart EXCOR®Dilated cardiomyopathyHeart failureHeart transplantationPaediatric ventricular assist device

Identifiers

PMID41142293

DOI10.1007/s12055-025-01994-9

PMCPMC12549503

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