ReviewFrontiers in pharmacology2025
Research on the mechanisms of plant bioactive metabolites in anti-skin aging and future development prospects.
Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Article
- Stem Cells in Cosmetic Applications: Advancements, Challenges, and Future Directions.Journal of cosmetic dermatology · 2026Review
- Plant-Derived Bioactive Compounds: Antioxidation, Autophagy, and Translational Applications in Skin Protection.Current issues in molecular biology · 2026Review
- From Nature to Nanomedicine: Engineered Plant-Derived Nanovesicles for Skin Disease.International journal of nanomedicine · 2026Review
- Deciphering the Skin Anti-Aging and Hair Growth Promoting Mechanisms ofInternational journal of molecular sciences · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With the accelerated pace of modern life and the influence of various environmental factors, skin aging has become a widespread health and aesthetic concern worldwide. Therefore, there is an urgent need for safe, effective and cost-efficient options for the prevention and treatment of skin aging. Researchers have been actively exploring anti-skin aging metabolites that can replace synthetic chemical agents. In recent years, natural plant bioactive metabolites isolated from plants have been considered as good alternatives and have been favored by an increasing number of researchers due to their rich content of bioactive metabolites and low side effects. Botanical bioactive metabolites have become a focal point in the field of anti-aging skincare due to their effectiveness in alleviating visible signs of skin aging and their potential to enhance the overall health of the skin. We collected relevant literature published between 2010 and 2025 using keywords such as "skin aging," "plant bioactive metabolites," "antioxidant," "reactive oxygen species," "matrix metalloproteinases," "inflammation," and others. This review describes skin aging, common plant (e.g., rice, ginseng, tea, etc.) bioactive metabolites and their efficacy and mechanism of action in delaying skin aging. In addition, the development potential and future trends of botanical bioactive metabolites are explored with the aim of providing a more holistic approach to skin aging care and offering valuable insights into the use of botanical bioactive metabolites as important metabolites in the formulation of anti-aging products.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.