Evidence map›Paper›PMID 41142210›Full record

ArticleResuscitation plus2025

Urban-rural disparities in out-of-hospital cardiac arrest outcomes: a nationwide Hungarian study.

Ádám Pál-Jakab, Bettina Nagy, Boldizsár Kiss, György Pápai, Nora Boussoussou, Béla Merkely, Miklós Constantinovits, Gábor Csató, Péter Sótonyi, Brigitta Szilágyi and 1 more

Abstract read
In one paragraph

Article in Resuscitation plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Ádám Pál-JakabHeart and Vascular Centre, Semmelweis University, 1122 Budapest, Hungary.
Bettina NagyHeart and Vascular Centre, Semmelweis University, 1122 Budapest, Hungary.
Boldizsár KissHeart and Vascular Centre, Semmelweis University, 1122 Budapest, Hungary.
György PápaiHungarian National Ambulance Service (HNAS), Markó Street 22., 1055 Budapest, Hungary.
Nora BoussoussouHeart and Vascular Centre, Semmelweis University, 1122 Budapest, Hungary.
Béla MerkelyHeart and Vascular Centre, Semmelweis University, 1122 Budapest, Hungary.
Miklós ConstantinovitsHungarian National Ambulance Service (HNAS), Markó Street 22., 1055 Budapest, Hungary.
Gábor CsatóHungarian National Ambulance Service (HNAS), Markó Street 22., 1055 Budapest, Hungary.
Péter SótonyiHeart and Vascular Centre, Semmelweis University, 1122 Budapest, Hungary.
Brigitta SzilágyiBudapest University of Technology and Economics, Műegyetem rkp. 3, 1111 Budapest, Hungary.
Endre ZimaHeart and Vascular Centre, Semmelweis University, 1122 Budapest, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Out-of-hospital cardiac arrest (OHCA) outcomes often differ between urban and rural settings, but comprehensive nationwide data from Central-Eastern Europe using uniform data collection and modern confounding control remain limited. We investigated urban-rural disparities in OHCA outcomes in Hungary. Methods: We analysed 130,258 OHCA cases (2018-2023) from the Hungarian National Ambulance Service registry, classified as urban (70.1 %) or rural (29.9 %) using national administrative categories. The primary outcome was on-scene return of spontaneous circulation (ROSC). We performed univariable and multivariable logistic regression, propensity score matching (PSM) and continuous response-time modeling using natural cubic splines. Results: The overall ROSC rate was 9.1 % (urban: 9.4 %, rural: 8.3 %, p < 0.001). After PSM, urban location remained significantly associated with higher survival (OR = 1.26, 95 % CI 1.20-1.32, p < 0.001). EMS response times were significantly longer in rural areas (median 14.9 vs 9.8 min, p < 0.001). Urban survival advantage was most pronounced in cases with shockable rhythms (OR = 1.57, 95 % CI 1.43-1.72), medical-witnessed arrests (OR = 1.31, 95 % CI 1.20-1.42), and response times ≤8 min (OR = 1.59, 95 % CI 1.44-1.76). Conclusions: Significant urban-rural disparities in OHCA on-scene ROSC persist even after accounting for patient and arrest characteristics. These findings highlight the need for targeted interventions to strengthen the Chain of Survival in rural communities.

Indexed as

Cardiac arrest (CA)Cardiopulmonary resuscitation (CPR)Emergency medical services (EMS)Out-of-hospital cardiac arrest (OHCA)Urban-rural disparity

Identifiers

PMID41142210
PMCPMC12546963

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.