Locally advanced primary urethral carcinoma in an HIV-positive female patient: report of a case successfully managed with definitive concurrent chemoradiotherapy at a referral cancer center in Abidjan.

Evrard Narcisse Séka, Corneille Téa Saki, Amara Gozana Tuo, Paul Hyacinthe Foua Bi

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Article in Urology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 authors.

Evrard Narcisse SékaDepartment of Radiotherapy, Alassane Ouattara National Center for medical oncology and Radiotherapy, 08 BP 4104 Abidjan 08, Abidjan-Cocody, Côte d'Ivoire.

Corneille Téa SakiDepartment of gynecology and obstetrics, Treichville hospital and university center, 01 BP V3 Abidjan 01 Treichville Marseille boulevard, Abidjan, Côte d'Ivoire.

Amara Gozana TuoDepartment of Radiotherapy, Alassane Ouattara National Center for medical oncology and Radiotherapy, 08 BP 4104 Abidjan 08, Abidjan-Cocody, Côte d'Ivoire.

Paul Hyacinthe Foua BiDepartment of Radiotherapy, Alassane Ouattara National Center for medical oncology and Radiotherapy, 08 BP 4104 Abidjan 08, Abidjan-Cocody, Côte d'Ivoire.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Female Primary urethral carcinoma is a rare malignancy frequently diagnosed at an advanced stage. Surgery, the most common treatment modality, is associated with substantial functional impairment. Here, we present the case of a 45-year-old HIV-positive woman with locally advanced squamous cell carcinoma infiltrating the bladder, vagina, and left obturator muscle, treated with definitive concurrent chemoradiotherapy combining fractionated external beam radiotherapy and weekly cisplatin. The treatment resulted in complete remission, which was sustained after 25 months of follow-up. This case supports the effectiveness of definitive concurrent chemoradiotherapy as an organ-preserving approach for advanced female squamous cell carcinoma of urethra.

Indexed as

Concurrent chemoradiotherapyHIV-PositiveOrgan preservationSquamous cell carcinoma of female Urethra

Identifiers

PMID41142185

DOI10.1016/j.eucr.2025.103239

PMCPMC12549707

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