Evidence map›Paper›PMID 41142141›Full record

ArticleJTO clinical and research reports2025

Lobectomy Induces Exercise-Induced Pulmonary Hypertension and Effort Intolerance Compared With Sublobar Resection.

Atsushi Kamigaichi, Yasuhiro Tsutani, Akane Tsuchiya, Hiroto Utsunomiya, Yoshihiro Miyata, Takahiro Mimae, Norifumi Tsubokawa, Yukiko Nakano, Morihito Okada

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In one paragraph

Article in JTO clinical and research reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Pulmonary vascular changes after lung resection: why less may be more.General thoracic and cardiovascular surgery · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Atsushi KamigaichiDepartment of Surgical Oncology, Hiroshima University, Hiroshima, Japan.
Yasuhiro TsutaniDivision of Thoracic Surgery, Department of Surgery, Kindai University, Osaka, Japan.
Akane TsuchiyaDepartment of Cardiovascular Medicine, Hiroshima University, Hiroshima, Japan.
Hiroto UtsunomiyaDepartment of Cardiovascular Medicine, Hiroshima University, Hiroshima, Japan.
Yoshihiro MiyataDepartment of Surgical Oncology, Hiroshima University, Hiroshima, Japan.
Takahiro MimaeDepartment of Surgical Oncology, Hiroshima University, Hiroshima, Japan.
Norifumi TsubokawaDepartment of Surgical Oncology, Hiroshima University, Hiroshima, Japan.
Yukiko NakanoDepartment of Cardiovascular Medicine, Hiroshima University, Hiroshima, Japan.
Morihito OkadaDepartment of Surgical Oncology, Hiroshima University, Hiroshima, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The rationale underlying the benefits of the parenchyma-preserving nature of sublobar resection (SR) compared with lobectomy remains unclear. This study aimed to assess postoperative changes in cardiopulmonary function after lobectomy and SR using exercise stress testing. Methods: This prospective, observational study enrolled patients scheduled for lobectomy or SR. Changes in cardiopulmonary function at 6 months postoperatively were evaluated using exercise stress echocardiography and cardiopulmonary exercise tests. Results: Initially, 41 patients were enrolled, with 20 patients in the lobectomy group and 18 patients in the SR group (16 segmentectomies, two wedge resections) after excluding three ineligible patients. Preoperatively, all patients demonstrated well-preserved cardiopulmonary function. The systolic pulmonary artery pressure (SPAP) change at peak exercise was significantly higher for lobectomy (median 26.5%; interquartile range [IQR] 0.6-60.1) than for SR (median -8.2%; IQR -38.7-11.7; Conclusions: Lobectomy induces increased SPAP during exercise, exPH, and effort intolerance, compared with SR. This highlights the importance of preserving lung parenchyma in lung surgery. Clinical Trial Registration: This trial is registered in the UMIN Clinical Trials Registry under the code UMIN000053694.

Indexed as

Cardiopulmonary exercise testExercise stress echocardiographyLobectomyPulmonary hypertensionSublobar resection

Identifiers

PMID41142141
PMCPMC12547739

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.