Evidence map›Paper›PMID 41142064›Full record

ArticleBiotechnologia2025

Demy Valerie Chacon, Kiana Alika Co, Daphne Noreen Enriquez, Aubrey Love Labarda, Reanne Eden Manongsong, Edward Kevin Bragais

Abstract read
In one paragraph

Article in Biotechnologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Demy Valerie ChaconDepartment of Biology, School of Science and Engineering, Ateneo de Manila University, Quezon City, Philippines.
Kiana Alika CoDepartment of Biology, School of Science and Engineering, Ateneo de Manila University, Quezon City, Philippines.
Daphne Noreen EnriquezDepartment of Biology, School of Science and Engineering, Ateneo de Manila University, Quezon City, Philippines.
Aubrey Love LabardaDepartment of Biology, School of Science and Engineering, Ateneo de Manila University, Quezon City, Philippines.
Reanne Eden ManongsongDepartment of Biology, School of Science and Engineering, Ateneo de Manila University, Quezon City, Philippines.
Edward Kevin BragaisDepartment of Biology, School of Science and Engineering, Ateneo de Manila University, Quezon City, Philippines.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Materials and methods: The protein variability server was utilized for conservation analysis. The epitopes were screened for antigenicity, allergenicity, toxicity, cross-reactivity, and population coverage. Selected epitopes were docked with their corresponding human leukocyte antigen (HLA) alleles, and thermodynamic quantities were determined. Five virulence factors - HopZ, SabA, HP-NAP, OipA, and urease - were selected for their critical roles in bacterial adhesion, immune modulation, and stress survival. Results: Conservation analysis revealed a highly conserved protein sequence (Shannon index ≤ 0.1). The predicted epitopes had an IC Conclusion: The epitopes predicted from the five virulence factors present promising candidates for future

Indexed as

cytotoxic T lymphocytesepitopesHelicobacter pyloriimmunoinformatics

Identifiers

PMID41142064
PMCPMC12550678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.