ReviewPain research & management2025
Radiofrequency and Cryoneurolysis in Pain Management: Development, Technique, and Application.
Review in Pain research & management, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Greater occipital nerve iatrogenic neuroma after cervical arthrodesis: high-frequency ultrasound findings and ultrasound-guided management.Skeletal radiology · 2026Article
- Emerging Nonpharmacologic Analgesic Technologies in Anesthesia: Mechanisms, Evidence, and Future Directions for Pharmacologic Alternatives.Biomedicines · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Radiofrequency and cryoneurolysis are promising options for managing chronic and acute pain. These minimally invasive techniques target nerve structures to alleviate pain in various conditions. This narrative review aims to provide an overview of the historical development, current techniques, applications, and existing evidence for radiofrequency and cryoneurolysis in pain management. While research is ongoing, evidence suggests their effectiveness in treating conditions like postmastectomy pain, phantom limb pain, radicular pain, and trigeminal neuralgia. However, their adoption in clinical guidelines varies, and they carry potential risks. Healthcare professionals should carefully consider the benefits, risks, and current evidence base when making treatment decisions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.