Evidence map›Paper›PMID 41142035›Full record

ArticleEuropean urology open science2025

Risk of Urinary Tract Infection with Perineal Urethrostomy Versus Urethroplasty.

Yishai H Rappaport, Nir Rahav, Boris Chertin, Ofer Z Shenfeld

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In one paragraph

Article in European urology open science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Yishai H RappaportCenter for Reconstructive and Functional Urology, Shaare Zedek Medical Center, Hadassah School of Medicine, Hebrew University, Jerusalem, Israel.
Nir RahavCenter for Reconstructive and Functional Urology, Shaare Zedek Medical Center, Hadassah School of Medicine, Hebrew University, Jerusalem, Israel.
Boris ChertinDepartment of Urology, Shaare Zedek Medical Center, Hadassah School of Medicine, Hebrew University, Jerusalem, Israel.
Ofer Z ShenfeldCenter for Reconstructive and Functional Urology, Shaare Zedek Medical Center, Hadassah School of Medicine, Hebrew University, Jerusalem, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective: Perineal urethrostomy (PU) is performed for urethral strictures in patients with high risk and those with complex strictures, such as after failure of urethroplasty. After PU, the neourethral meatus is located in the perineum in proximity to the anus, which may theoretically increase the risk of urinary tract infection (UTI). Our aim was to examine UTI rates among PU patients. Methods: Medical records for PU patients between 2004 and 2023 were analyzed for UTI incidence. A control group comprised patients with similar complex urethral strictures who underwent substitution or augmented urethroplasty. The primary endpoint was the incidence of recurrent UTI (rUTI), defined according to the European Association of Urology guidelines, or the use of prophylactic treatment for UTI. Data for chronic asymptomatic bacteriuria, UTI events, and urethral dilation were recorded. Analyses included t tests and Wilcoxon signed-rank tests for continuous variables, and Fisher's exact test for categorical variables. Key findings: There were 67 patients in the PU group and 66 in the control group, with median age of 51 yr (interquartile range 39-61) and 42 yr (interquartile range 29-58), respectively. Follow up was 32 mo for the PU group and 76 mo for the control group. The rUTI incidence rate was 21% in both groups. Repeat urethral dilation was required in five patients in the PU group and six in the control group ( Conclusions and clinical implications: PU does not increase the risk of UTI in comparison to urethroplasty for complex urethral strictures. Patients summary: We looked at the rate of urinary tract infection after two different surgical treatments (called perineal urethrostomy [PU] and urethroplasty [UTP]) for complex urethral stricture in men, which is a narrowing of the tube draining urine from the bladder. Infection rates did not differ between the PU and UTP techniques, but were higher than in the general population. When choosing between treatment options for this condition, the PU technique does not have higher risk of urinary tract infection than UTP.

Indexed as

Perineal urethrostomyRecurrentUrethroplastyUrinary tract infection

Identifiers

PMID41142035
PMCPMC12552564

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.