Evidence map›Paper›PMID 41141978›Full record

ReviewEJVES vascular forum2025

Endovascular Treatment of a Bilateral Phlegmasia Caerulea Dolens in a Two Year Old Child With Inferior Vena Cava Atresia: Case Report and Literature Review.

Marco Fresa, Aurel Vassili Njami, Ophélie De Pury, Rafael Trunfio, Mattia Rizzi, Adrien De Cock, Guillaume Maître, Lucia Mazzolai

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in EJVES vascular forum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marco FresaAngiology Department, Centre for Malformation and Rare Vascular Diseases, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Aurel Vassili NjamiAngiology Department, Centre for Malformation and Rare Vascular Diseases, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Ophélie De PuryPaediatric Intensive Care Department, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Rafael TrunfioVascular Surgery Department, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Mattia RizziHaematology Department, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Adrien De CockAnaesthetics Department, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Guillaume MaîtrePaediatric Intensive Care Department, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Lucia MazzolaiAngiology Department, Centre for Malformation and Rare Vascular Diseases, Lausanne University Hospital (CHUV), Lausanne, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Phlegmasia caerulea dolens (PCD) is a rare and potentially life threatening complication of deep vein thrombosis. It is more commonly reported in adult patients and rarely in the paediatric population, especially in healthy children. This review describes the case of a child with PCD and reviews the few cases of paediatric PCD previously reported in the literature. Methods: A search of the Medline database was performed with the purpose of identifying other similar cases and treatment modalities. Results: This study describes the case of a child with PCD in the setting of an atretic inferior vena cava, who was successfully treated with endovascular mechanical thrombectomy (Indigo Lightning Penumbra aspiration catheter) and intraluminal recanalisation and venoplasty of the inferior vena cava, with full recovery and no sequelae after 12 months of follow up. Conclusion: The use of mechanical thrombectomy in the setting of severe acute deep vein thrombosis is well established in adults, but not in children. Moreover, the recanalisation of an atretic inferior vena cava in such a young patient has not been described previously. The clinical outcome of this threatening condition was favourable, confirming that modern endovascular techniques for the venous system may also apply to the paediatric population and help deal with similar situations in this subset of patients.

Indexed as

Acute deep vein thrombosisEndovascularPhlegmasiaVena cava atresiaVenous

Identifiers

PMID41141978
PMCPMC12547872

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.