Evidence map›Paper›PMID 41141958›Full record

ArticleAJPM focus2025

Real-World Interventions for Type 2 Diabetes Prevention (REALITY): A Multisite Study to Assess the Effectiveness and Cost-Effectiveness of the National Diabetes Prevention Program.

William H Herman, Benjamin D Tyndall, O Kenrik Duru, Tannaz Moin, Laura N McEwen, Hui Shao, Ronald T Ackermann, Sara R Jacobs, Simon Neuwahl, Shihchen Kuo and 4 more

Abstract read
In one paragraph

Article in AJPM focus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

William H HermanDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan.
Benjamin D TyndallHealth Practice Area, RTI International, Research Triangle Park, North Carolina.
O Kenrik DuruDivision of General Internal Medicine & Health Services Research, University of California Los Angles, Los Angles, California.
Tannaz MoinDivision of General Internal Medicine & Health Services Research, University of California Los Angles, Los Angles, California.
Laura N McEwenDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
Hui ShaoDepartment of Global Health, Emory University School of Medicine, Atlanta, Georgia.
Ronald T AckermannDepartment of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Sara R JacobsHealth Practice Area, RTI International, Research Triangle Park, North Carolina.
Simon NeuwahlHealth Practice Area, RTI International, Research Triangle Park, North Carolina.
Shihchen KuoDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
Ping ZhangEpidemiology and Statistics Branch, Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, Georgia.
Meda E PavkovEpidemiology and Statistics Branch, Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, Georgia.
Claudia Villatoro SantosDivision of Endocrinology, Washington University in St. Louis, St. Louis, Missouri.
REALITY Network

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
NCCDPHP CDC HHS U18 DP006707NCCDPHP CDC HHS U18 DP006709NIDDK NIH HHS P30 DK020572
6 · The paper itself

Abstract

Introduction: The National Diabetes Prevention Program was created on the basis of evidence from landmark clinical trials. Its format was modified to facilitate real-world delivery. The long-term effectiveness and cost-effectiveness of the National Diabetes Prevention Program and similar lifestyle change programs in real-world settings remain largely unknown. The Centers for Disease Control and Prevention issued a request for proposals to establish and fund a research network to determine the long-term effectiveness of the National Diabetes Prevention Program in reducing Type 2 diabetes incidence, improving cardiovascular disease risk factors and health-related quality of life, and reducing healthcare service utilization and costs. Methods: Researchers at the University of California Los Angeles, Northwestern University, the University of Michigan, and Emory University, with a coordinating center at RTI International, were funded to examine incident Type 2 diabetes and cardiovascular disease risk factors among a diverse group of National Diabetes Prevention Program and MOVE! enrollees and nonenrollees using electronic health record and administrative claims data. The network will also assess health utility scores by conducting a health-related quality of life survey; examine healthcare utilization, costs, and cost-effectiveness of the National Diabetes Prevention Program and MOVE! for diabetes prevention; and assess the costs of delivering these programs. Results: The study sites have collaborated with RTI and Centers for Disease Control and Prevention to develop common core data elements and standardized study procedures to ensure that each site collects data that can be harmonized across sites. Conclusions: The results of this research will address the objectives of

Indexed as

cost-effectivenessdiabetes preventionlifestyle change programsMOVE!National Diabetes Prevention ProgramPrediabetes

Identifiers

PMID41141958
PMCPMC12550230

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.