Evidence map›Paper›PMID 41141841›Full record

ReviewAmerican heart journal plus : cardiology research and practice2025

Treatment outcome and associated factors of acute heart failure in East Africa, an Ethiopian perspective: A systematic review and meta-analysis.

Asnake Gashaw Belayneh, Getnet Alemu Andargie, Kedir Seid, Gebeyehu Lakew, Amlaku Nigusie Yirsaw, Mitiku Tefera, Eyob Ketema Bogale, Tadele Fentabel Anagaw, Eneyew Talie Fenta, Destaw Endeshaw and 5 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in American heart journal plus : cardiology research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Asnake Gashaw BelaynehDepartment of Emergency and Critical Care Nursing, College of Medicine and Health Science, Bahir Dar University, P.O. Box 79, Bahir Dar, Ethiopia.
Getnet Alemu AndargieDepartment of Nutrition, Antsokiya Gemza wereda Health Office, North Shoa, Ethiopia.
Kedir SeidBati Primary Hospital, Oromia Special Zone, North Shoa, Ethiopia.
Gebeyehu LakewDepartment of Health Promotion and Health Behavior, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, PO. Box.196, Gondar, Ethiopia.
Amlaku Nigusie YirsawDepartment of Health Promotion and Health Behavior, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, PO. Box.196, Gondar, Ethiopia.
Mitiku TeferaDepartment of Midwifery, School of Nursing and Midwifery, Asrat woldeyes health science campus, Debre Berehan University, Ethiopia.
Eyob Ketema BogaleHealth Promotion and Behavioral Science Department, School of Public Health, College of Medicine and Health Science, Bahir Dar University, Bahir Dar, Ethiopia.
Tadele Fentabel AnagawHealth Promotion and Behavioral Science Department, School of Public Health, College of Medicine and Health Science, Bahir Dar University, Bahir Dar, Ethiopia.
Eneyew Talie FentaDepartment of public health, College of Medicine and Health Science, Injibara University, Injibara, Ethiopia.
Destaw EndeshawDepartment of Adult Health Nursing, School of Health Sciences, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
Ousman AdalDepartment of Emergency and Critical Care Nursing, College of Medicine and Health Science, Bahir Dar University, P.O. Box 79, Bahir Dar, Ethiopia.
Abiyu Abadi TarekeAmref health Africa in Ethiopia, SLL project, COVID-19 vaccine/EPI technical assistant at West Gondar zonal health department, Ethiopia.
Natnael KebedeDepartment of Health Promotion, School of Public health College of Medicine Health Sciences, Wollo University, Dessie, Ethiopia.
Lijalem JemberuTibebe Ghion Specialized Hospital, Bahir Dar University, Ethiopia.
Eyob GetachewDepartment of Health Promotion and Health Behavior, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, PO. Box.196, Gondar, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute heart failure is a major global health issue, contributing to significant morbidity, mortality, and healthcare costs in Sub-Saharan Africa, including Ethiopia. Despite its burden, comprehensive data on acute heart failure in East Africa remains scarce. Objective: This systematic review and meta-analysis aimed to synthesize existing evidence on the treatment outcome of acute heart failure and associated factors in East Africa with a focus on Ethiopia. Methods: Relevant studies were searched in major databases, including PubMed/Medline, Hinari, Science Direct, EMBASE, Scopus, AJOL, Cochrane Library, and local sources from July 5-25, 2024. Both published and unpublished studies in English were included without restrictions on publication date, following PRISMA-2020 protocols. Data quality was assessed using the Newcastle-Ottawa Scale, and meta-analysis was conducted using Stata version 18. Results: A total of 9 articles involving 1107 participants were included. The pooled mortality of acute heart failure was 16.36 % (95 % CI: 12.39, 20.33) with heterogeneity (I Conclusion: This review reveals a high mortality of acute heart failure among hospitalized patients in Ethiopia. Factors such as increased blood urea nitrogen (BUN), smoking, and hypotension contribute to death due to acute heart failure. Therefore, it is necessary to reduce the burden of acute heart failure and improve patient survival in Ethiopia by addressing the identified predictors of poor outcomes and integrating global best practices into local healthcare systems.

Indexed as

Acute heart failureEthiopiaMeta-analysisMortalitySystematic reviewTreatment outcome

Identifiers

PMID41141841
PMCPMC12552915

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.