Evidence map›Paper›PMID 41141705›Full record

SynthesisFrontiers in surgery2025

Comparative analysis of postoperative outcomes following surgical and transcatheter edge-to-edge mitral valve repair for secondary mitral regurgitation: a meta-analysis & systematic review.

Dudy A Hanafy, Adrian R Sudirman, Sari Rahmawati, Hendry R Satria, Safitri, Stefanus Nursalim, Muhammad R Bachmid, Dwi G Fardhani, Tri W Soetisna, Sugisman

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dudy A HanafyDepartment of Cardiac, Thoracic, and Vascular Surgery, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia.
Adrian R SudirmanDepartment of Cardiac, Thoracic, and Vascular Surgery, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia.
Sari RahmawatiDepartment of Cardiac, Thoracic, and Vascular Surgery, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia.
Hendry R SatriaDepartment of Cardiac, Thoracic, and Vascular Surgery, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia.
SafitriDepartment of Cardiac, Thoracic, and Vascular Surgery, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia.
Stefanus NursalimDepartment of Cardiac, Thoracic, and Vascular Surgery, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia.
Muhammad R BachmidDepartment of Cardiac, Thoracic, and Vascular Surgery, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia.
Dwi G FardhaniDepartment of Cardiac, Thoracic, and Vascular Surgery, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia.
Tri W SoetisnaDepartment of Cardiac, Thoracic, and Vascular Surgery, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia.
SugismanDepartment of Cardiac, Thoracic, and Vascular Surgery, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Mitral regurgitation (MR) affects approximately millions of people globally, predominantly older adults, leading to 0.88 million DALY and 34,000 deaths in 2019. Both ESC and ACC/AHA guidelines recommend intervention either surgery or transcatheter for secondary MR despite optimal medical therapy. The comparative effectiveness of SMVr vs. TEER for managing secondary MR remains uncertain, prompting a systematic review to assess outcomes, safety, and long-term implications. Method: This systematic review and meta-analysis were carried out and documented according to the PRISMA 2020 guidelines. Searches were conducted in the Embase, EBSCOHost, Medline, Sage, Science Direct, and Scopus databases. Result: This meta-analysis included eight studies and 6224 patients. Both SMVr and TEER showed similar rate of in-hospital mortality (3.85% vs. 2.83%, RR = 2.54; 95% CI = 0.59-10.95; Conclusion: SMVr has demonstrated better mid-term outcomes than TEER, including lower mortality rates, fewer reinterventions and rehospitalization, and improved functional status in patients with mitral regurgitation. Systematic Review Registration: identifier [CRD42024538771].

Indexed as

mitral regurgitationmitral valve repairsecondary MRsurgicaltranscatheter

Identifiers

PMID41141705
PMCPMC12546329

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.