Evidence map›Paper›PMID 41141655›Full record

ArticleClinical and translational radiation oncology2026

Therapeutic efficacy of external beam radiotherapy combined with anti-PD-L1 inhibition in a preclinical syngeneic head and neck cancer model.

Arshiya Banu, Sophie Langdon, Tanzila Harun, Adam Laouafa, Adam Jones, Kavitha Sunassee, Anthony Kong, Samantha Ya Terry

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational radiation oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Arshiya BanuSchool of Biomedical Engineering and Imaging Sciences, King's College London, London SE1 7EH, UK.
Sophie LangdonSchool of Biomedical Engineering and Imaging Sciences, King's College London, London SE1 7EH, UK.
Tanzila HarunSchool of Biomedical Engineering and Imaging Sciences, King's College London, London SE1 7EH, UK.
Adam LaouafaSchool of Biomedical Engineering and Imaging Sciences, King's College London, London SE1 7EH, UK.
Adam JonesSchool of Biomedical Engineering and Imaging Sciences, King's College London, London SE1 7EH, UK.
Kavitha SunasseeSchool of Biomedical Engineering and Imaging Sciences, King's College London, London SE1 7EH, UK.
Anthony KongFaculty of Life Sciences and Medicine, King's College London, London SE1 9RT, UK.
Samantha Ya TerrySchool of Biomedical Engineering and Imaging Sciences, King's College London, London SE1 7EH, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treating high-grade head and neck squamous cell carcinoma (HNSCC) has recently combined immunotherapy with conventional therapies. However, optimizing the scheduling of anti-PD-L1 with external beam radiation therapy (EBRT) requires further research to improve efficacies. Methods: Results: MTCQ1 cells exhibited the most marked responses to EBRT Conclusion: These results reveal spatial distribution of immune cells in the tumor microenvironment and underscore the role of EBRT regimens in modulating immune cell dynamics. This highlights the importance of optimising radiation protocols to inform combination therapy designs in preclinical models.

Indexed as

Head and neck cancerImmune cellsImmune checkpoint inhibitionRadiobiologyTargeted external beam radiotherapy

Identifiers

PMID41141655
PMCPMC12550321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.