Evidence map›Paper›PMID 41141618›Full record

ArticleBiochemistry and biophysics reports2025

Enhanced isoprenoid production in

Takuya Takahashi, Takuya Saito, Irori Dohgami, Tomokazu Ito, Hisashi Hemmi

Erratum issuedAbstract read
In one paragraph

Article in Biochemistry and biophysics reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Takuya TakahashiDepartment of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi, 460-8601, Japan.
Takuya SaitoDepartment of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi, 460-8601, Japan.
Irori DohgamiDepartment of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi, 460-8601, Japan.
Tomokazu ItoDepartment of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi, 460-8601, Japan.
Hisashi HemmiDepartment of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi, 460-8601, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbial production of isoprenoids has attracted interest as a white biotechnology approach that yields valuable compounds, such as medicinal, biofuel, and sustainable industrial materials. Enhancement of isoprenoid production in microbial cells has been achieved through metabolic engineering, usually by exploiting one of the biosynthetic pathways supplying the precursors for isoprenoids, i.e., isopentenyl diphosphate and dimethylallyl diphosphate. The pathways used include the naturally occurring mevalonate (MVA) and methylerythritol phosphate (MEP) pathways, and the artificial isoprenol/prenol utilization pathway. Among them, the introduction of the MVA pathway has been extensively studied and has actually been used to enhance the isoprenoid productivity of bacteria that intrinsically exhibit the MEP pathway, such as

Indexed as

ArchaeaCarotenoidIsoprenoidMevalonate pathwayTerpene

Identifiers

PMID41141618
PMCPMC12547664

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.