Evidence map›Paper›PMID 41141513›Full record

ArticleKidney international reports2025

Intraarterial Autologous Mesenchymal Stem Cell Therapy for Diabetic Kidney Disease.

Lina S Alatta, Khaled M Elhusseiny, Allan B Dietz, Sandra M Herrmann, Elizabeth C Lorenz, Donna K Lawson, Emily C Bendel, Chris J Reisenauer, Sanjay Misra, Lisa E Vaughan and 2 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Kidney international reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03840343 (Intra-arterially Delivered Autologous Mesenchymal Stem/Stromal Cell Therapy in Patients With Diabetic Kidney Disease), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03840343 phase1terminatednot on this map

Intra-arterially Delivered Autologous Mesenchymal Stem/Stromal Cell Therapy in Patients With Diabetic Kidney Disease: A Phase I Study

TypeinterventionalSponsorMayo ClinicRan2019 to 2020Enrolled2ConditionsDiabetic Kidney Disease, Diabetic Nephropathies, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1ArmsAutologous adipose-derived mesenchymal stem/stromal cells (MSC) Lower Dose, Autologous adipose-derived mesenchymal stem/stromal cells (MSC) Higher Dose
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lina S AlattaDivision of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Jacksonville, Florida, USA.
Khaled M ElhusseinyDivision of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Jacksonville, Florida, USA.
Allan B DietzDepartment of Lab Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Sandra M HerrmannDivision of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Elizabeth C LorenzDivision of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Donna K LawsonHospital Internal Medicine Research, Mayo Clinic, Rochester, Minnesota, USA.
Emily C BendelVascular and Interventional Radiology, Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Chris J ReisenauerVascular and Interventional Radiology, Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Sanjay MisraVascular and Interventional Radiology, Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Lisa E VaughanDepartment of Quantitative Health Sciences, Clinical Trials and Biostatistics, Mayo Clinic, Rochester, Minnesota, USA.
Lilach O LermanDivision of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
LaTonya J HicksonDivision of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Jacksonville, Florida, USA.

Funding

Extracellular vesicle-based senotherapeutics for aging diabetic kidneydiseaseR01AG076537 · NIA · MAYO CLINIC JACKSONVILLE · PI LaTonya J Hickson · 2023 to 2026
$2.3M
NIA NIH HHS R01 AG076537
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

autologouschronic kidney diseasediabetes mellituskidney functionregenerative medicinesafety

Identifiers

PMID41141513
PMCPMC12545884

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.