Evidence map›Paper›PMID 41141387›Full record

ArticleGenes & diseases2026

Chang Liu, Hongyan Yuan, Jindie Huang, Shidian Ran, Xiaorui Wei, Xingrui Yan, Linyu Xue, Tong-Chuan He, Yuxin Zhang, Mengqin Gu and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes & diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Chang LiuChongqing Key Laboratory for Oral Diseases, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing 401147, China.
Hongyan YuanChongqing Key Laboratory for Oral Diseases, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing 401147, China.
Jindie HuangChongqing Key Laboratory for Oral Diseases, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing 401147, China.
Shidian RanChongqing Key Laboratory for Oral Diseases, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing 401147, China.
Xiaorui WeiChongqing Key Laboratory for Oral Diseases, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing 401147, China.
Xingrui YanChongqing Key Laboratory for Oral Diseases, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing 401147, China.
Linyu XueChongqing Key Laboratory for Oral Diseases, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing 401147, China.
Tong-Chuan HeMolecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, IL 60637, USA.
Yuxin ZhangChongqing Key Laboratory for Oral Diseases, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing 401147, China.
Mengqin GuChongqing Key Laboratory for Oral Diseases, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing 401147, China.
Si WuChongqing Key Laboratory for Oral Diseases, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing 401147, China.
Fugui ZhangChongqing Key Laboratory for Oral Diseases, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing 401147, China.
Wenping LuoLaboratory Animal Center of Southwest University, Chongqing 400799, China.
Hongmei ZhangChongqing Key Laboratory for Oral Diseases, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing 401147, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tooth formation is a highly orchestrated process that precisely regulates the size and shape of the tooth. During typical tooth development, Hertwig's epithelial root sheath (HERS) interacts with mesenchymal cells to direct the elongation of the tooth root and the deposition of dentin and cementum, thereby contributing to the formation of a fully developed tooth root. BMP9, a member of the BMP family, plays a significant role in growth, development, and cell differentiation. However, the precise function of BMP9 in dental root development remains unclear, particularly regarding its influence on HERS and odontoblasts. In this study, we utilized a mouse molar model to investigate the role of BMP9 signaling in tooth root development. The tooth formation of

Indexed as

Bone morphogenetic protein 9DentinogenesisHertwig's epithelial root sheathOdontoblastic differentiationTooth root development

Identifiers

PMID41141387
PMCPMC12552948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.