Evidence map›Paper›PMID 41141376›Full record

ArticleJournal of immunology research2025

Atypical Phenotype of Predominant Autoimmune Cytopenia and Impaired Perforin Expression in XMEN Syndrome.

Hana Grombirikova, Adam Markocsy, Anna Kocurkova, Jan Blatny, Marcela Vlkova, Peter Slanina, Eva Hlavackova, Veronika Fiamoli, Helena Schneiderova, Adam Klocperk and 6 more

Abstract readCase Reports
In one paragraph

Article in Journal of immunology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Hana GrombirikovaCentre for Cardiovascular Surgery and Transplantation, Brno, Czech Republic, cktch.cz.ORCID https://orcid.org/0000-0002-9317-8531
Adam MarkocsyCentre for Primary Immunodeficiencies, Department of Paediatrics and Adolescent Medicine, Jessenius Faculty of Medicine, Comenius University in Bratislava, University Hospital in Martin, Martin, Slovakia, uniba.sk.ORCID https://orcid.org/0009-0006-4928-7673
Anna KocurkovaFaculty of Medicine, Masaryk University, Brno, Czech Republic, muni.cz.ORCID https://orcid.org/0000-0002-2752-2998
Jan BlatnyDepartment of Paediatric Haematology and Biochemistry of University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic, muni.cz.ORCID https://orcid.org/0000-0001-6261-9157
Marcela VlkovaFaculty of Medicine, Masaryk University, Brno, Czech Republic, muni.cz.ORCID https://orcid.org/0000-0003-2122-7784
Peter SlaninaFaculty of Medicine, Masaryk University, Brno, Czech Republic, muni.cz.
Eva HlavackovaFaculty of Medicine, Masaryk University, Brno, Czech Republic, muni.cz.ORCID https://orcid.org/0000-0002-8610-7540
Veronika FiamoliDepartment of Paediatric Haematology and Biochemistry of University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic, muni.cz.ORCID https://orcid.org/0000-0002-9545-3824
Helena SchneiderovaDepartment of Paediatrics, University Hospital Brno, Brno, Czech Republic, fnbrno.cz.ORCID https://orcid.org/0009-0007-9770-9938
Adam KlocperkDepartment of Immunology, 2nd Faculty of Medicine, Charles University and University Hospital in Motol, Prague, Czech Republic, cuni.cz.ORCID https://orcid.org/0000-0002-1526-4557
Dita RicnaCentre for Cardiovascular Surgery and Transplantation, Brno, Czech Republic, cktch.cz.ORCID https://orcid.org/0000-0001-5972-1118
Eva FronkovaCLIP Laboratory Centre, Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic, cuni.cz.ORCID https://orcid.org/0000-0002-6900-8145
Jan KralCentre for Medical Genetics and Reproductive Medicine, GENNET, Prague, Czech Republic.ORCID https://orcid.org/0000-0002-3877-1033
Anna SalingovaDepartment of Laboratory Medicine, Centre of Inherited Metabolic Diseases, National Institute of Children's Diseases, Bratislava, Slovakia.ORCID https://orcid.org/0009-0009-3289-5586
Milos JesenakCentre for Primary Immunodeficiencies, Department of Paediatrics and Adolescent Medicine, Jessenius Faculty of Medicine, Comenius University in Bratislava, University Hospital in Martin, Martin, Slovakia, uniba.sk.ORCID https://orcid.org/0000-0001-7976-2523
Tomas FreibergerCentre for Cardiovascular Surgery and Transplantation, Brno, Czech Republic, cktch.cz.ORCID https://orcid.org/0000-0001-6532-7053

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

X-linked immunodeficiency with magnesium defect, Epstein-Barr virus (EBV) infection, and neoplasia (XMEN) is caused by a pathogenic variant in the magnesium transporter 1 (

Indexed as

Autoimmune DiseasesCation Transport ProteinsEpstein-Barr Virus InfectionsPerforinX-Linked Combined Immunodeficiency DiseasesAdolescentAdultCD8-Positive T-LymphocytesChildChild, PreschoolCytopeniaFemaleHumansKiller Cells, NaturalMalePedigreeCation Transport ProteinsMagT1 protein, humanPerforinautoimmune cytopeniaautoimmune haemolytic anaemiacongenital disorders of glycosylationimmune thrombocytopeniaMAGT1perforinXMEN

Identifiers

PMID41141376
PMCPMC12551146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.