Evidence map›Paper›PMID 41141260›Full record

SynthesisFrontiers in nutrition2025

Impact of fermented foods consumption on gastrointestinal wellbeing in healthy adults: a systematic review and meta-analysis.

Arghya Mukherjee, Dominic N Farsi, Enriqueta Garcia-Gutierrez, Ecem Akan, Jose Angel Salas Millan, Ljupco Angelovski, Thomas Bintsis, Amaury Gérard, Ziba Güley, Sümeyye Kabakcı and 15 more

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Arghya MukherjeeDepartment of Food Biosciences, Teagasc, Fermoy, Cork, Ireland.
Dominic N FarsiHuman Nutrition Unit, INRAE, Université Clermont-Auvergne, Clermont-Ferrand, France.
Enriqueta Garcia-Gutierrez *Department of Food Biosciences, Teagasc, Fermoy, Cork, Ireland.
Ecem Akan *Department of Dairy Technology, Faculty of Agriculture, Adnan Menderes University, Aydın, Türkiye.
Jose Angel Salas Millan *APC Microbiome Ireland, Cork, Ireland.
Ljupco Angelovski *Faculty of Veterinary Medicine, University Ss Cyril and Methodius, Skopje, North Macedonia.
Thomas Bintsis *Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Amaury Gérard *Brewing and Food Science Unit, LABIRIS, Anderlecht, Belgium.
Ziba Güley *Department of Food Engineering, Alanya Alaaddin Keykubat University, Alanya, Türkiye.
Sümeyye Kabakcı *National Food Reference Laboratory, Ministry of Agriculture and Forestry, Ankara, Türkiye.
Minna Kahala *Productions Systems, Food and Bioproducts, Natural Resources Institute Finland (Luke), Helsinki, Finland.
Ryma Merabti *Faculty of Natural and Life Sciences, Department of Cellular and Molecular Biology, Abbes Laghrour University, Khenchela, Algeria.
Foteini Pavli *Department of Food Sciences and Nutrition, University of Malta, Msida, Malta.
Elisa Salvetti *Department of Biotechnology and Verona University Culture Collection (VUCC-DBT), University of Verona, Verona, Italy.
Cem KaragözlüDepartment of Dairy Technology, Ege University, Izmir, Türkiye.
Nurcan BağlamDepartment of Nutrition and Dietetics, Sivas Cumhuriyet University, Sivas, Türkiye.
Bahtir HyseniFaculty of Food Technology, University "Isa Boletini, Mitrovica, Republic of Kosovo.
Simona BavaroInstitute of the Sciences of Food Production, National Research Council, Turin, Italy.
Konstantinos PapadimitriouDepartment of Food Science and Human Nutrition, Agricultural University of Athens, Athens, Greece.
Eun-Hee DooDepartment of Yuhan Biotechnology, School of Bio-Health Sciences, Yuhan University, Bucheon, Republic of Korea.
Christophe ChassardUCA, INRAE, VetAgro Sup, UMRF, Aurillac, France.
Smilja PraćerInstitute for Biological Research Siniša Stanković, National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia.
Guy VergèresAgroscope, Bern, Switzerland.
Paul D CotterDepartment of Food Biosciences, Teagasc, Fermoy, Cork, Ireland.
Sandra MojsovaFaculty of Veterinary Medicine, University Ss Cyril and Methodius, Skopje, North Macedonia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: In recent years, the consumption of fermented foods (FFs) has been linked with gastrointestinal health and wellbeing. Here, we systematically review and meta-analyse the currently available evidence relating to this as part of the COST Action PIMENTO and guided by the European Food Safety Authority (EFSA) health claim dossiers. Methods: MEDLINE, Scopus and Cochrane CENTRAL bibliographic libraries were searched for relevant literature up to 31st January 2025. All eligible studies were included for narrative review as per EFSA guidelines, but only randomised controlled trials (RCTs) were considered for meta-analyses. Risk of bias, mechanisms of action, bioactive compounds and safety were additionally discussed. Data was pooled using mean difference (MD)/standardized MD for continuous data and relative risk (RR) for dichotomous data. Certainty of evidence was evaluated through GRADE assessment. Results: A total of 25 studies (19 RCTs included in meta-analysis) with 4,328 participants were included in the systematic review. Meta-analysis demonstrated the beneficial impact of FF consumption on frequency of bowel movements (MD 0.60, CI 0.04, 1.16, Conclusion: Our analysis suggests that FF consumption beneficially impacts the frequency of bowel movements, stool consistency, incidence of hard stools, intestinal transit time, abdominal symptoms, bloating, borborygmi, flatulence and degree of constipation. Systematic review registration: This study was registered at the Open Science Framework (osf.io, registration number: q8yzd).

Indexed as

bloatingconstipationfermented foodsflatulencegastrointestinal healthgut microbiomestool consistencystool frequency

Identifiers

PMID41141260
PMCPMC12549620

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.