Evidence map›Paper›PMID 41141185›Full record

ArticleCureus2025

Efficacy of the Semicircular Inverted Internal Limiting Membrane Flap Technique for Macular Hole Retinal Detachment in Hyperopic Eyes: A Case Series.

Masayuki Inuzuka, Masaomi Kubota, Norifumi Takaki, Toshio Hisatomi, Hirokazu Sakaguchi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Masayuki InuzukaDepartment of Ophthalmology and Visual Sciences, Gifu University, Graduate School of Medical Sciences, Gifu, JPN.
Masaomi KubotaDepartment of Ophthalmology and Visual Sciences, Gifu University, Graduate School of Medical Sciences, Gifu, JPN.
Norifumi TakakiDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JPN.
Toshio HisatomiDepartment of Ophthalmology and Visual Sciences, Gifu University, Graduate School of Medical Sciences, Gifu, JPN.
Hirokazu SakaguchiDepartment of Ophthalmology and Visual Sciences, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report anatomical and functional outcomes for three hyperopic phakic women with macular hole retinal detachment (MHRD) treated using a superiorly based semicircular inverted internal limiting membrane (ILM) flap. All patients underwent 25-gauge pars plana vitrectomy with Brilliant Blue G-assisted ILM manipulation, inversion of a superior semicircular flap to cover the macular hole, and 20% sulfur hexafluoride (SF₆) tamponade. Postoperative assessment included decimal best-corrected visual acuity (BCVA) and spectral-domain optical coherence tomography (OCT). All eyes achieved immediate macular hole closure, and complete retinal reattachment was attained after 18-24 months. Final BCVA improved in two eyes (from 0.1 to 0.4) and remained 0.2 in one eye, underscoring delayed but meaningful recovery in hyperopic MHRD treated with a semicircular inverted ILM flap. OCT demonstrated stepwise foveal restoration with variable ellipsoid zone/external limiting membrane (ELM/EZ) integrity across cases, and no intraoperative complications, macular hole reopening, or recurrent detachment were observed. These findings indicate that in hyperopic MHRD, a semicircular inverted ILM flap is feasible and mechanically reliable for early hole closure, while SRF absorption and functional recovery may require prolonged follow-up, likely reflecting the timeline of outer-retinal reconstruction.

Indexed as

hyperopiainverted internal limiting membrane flapmacular hole retinal detachmentoptical coherence tomographyouter retinal layer restorationpars plana vitrectomysemicircular ilm flap techniquesubretinal fluid absorption

Identifiers

PMID41141185
PMCPMC12552190

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