Evidence map›Paper›PMID 41141176›Full record

ArticleCureus2025

Incidental Diagnosis of Normal Pressure Hydrocephalus in Elderly Patients Presenting With Acute Neurological Illnesses: A Report of Two Cases.

Kyaw Z Aung, Naw Eh Law Saw, Ei Ei Cho, Cherry Myint, Han Thant Thant

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kyaw Z AungInternal Medicine Department, Kulhudhuffushi Regional Hospital, Kulhudhuffushi City, MDV.
Naw Eh Law SawInternal Medicine Department, Kulhudhuffushi Regional Hospital, Kulhudhuffushi City, MDV.
Ei Ei ChoInternal Medicine Department, Kulhudhuffushi Regional Hospital, Kulhudhuffushi City, MDV.
Cherry MyintEmergency Department, Kulhudhuffushi Regional Hospital, Kulhudhuffushi City, MDV.
Han Thant ThantEmergency Department, Kulhudhuffushi Regional Hospital, Kulhudhuffushi City, MDV.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Normal pressure hydrocephalus (NPH) is a potentially reversible neurological condition in older adults characterized by gait disturbance, cognitive decline, and urinary incontinence, but its diagnosis is frequently delayed or missed, especially when patients present with other acute medical issues. We report two illustrative cases where probable NPH was incidentally detected during hospitalization for unrelated acute presentations. In both instances, brain imaging performed for other diagnostic purposes revealed ventriculomegaly, and subsequent cerebrospinal fluid (CSF) analysis confirmed normal opening pressure and composition. Further history revealed previously unaddressed symptoms consistent with probable NPH. Although surgical intervention was not pursued due to advanced age, comorbidities, and patient or family preferences, the diagnosis allowed for informed decision-making and supportive care planning. These cases highlight how NPH may remain cryptic in elderly patients, especially when acute, self-limiting disorders dominate the clinical picture. They underscore the importance of maintaining a broad differential diagnosis and obtaining neuroimaging when chronic symptoms such as urinary incontinence, gait impairment, or cognitive decline are present, even when overshadowed by other diagnoses. Given that timely shunting can result in marked improvements in mobility, cognition, and bladder control in many patients, early identification is essential. At the same time, management of NPH must be individualized, taking into account patient age, comorbidities, surgical risks, and personal or family preferences. In both cases, while definitive intervention was not pursued, awareness of the diagnosis enabled informed shared decision-making and offered targeted long-term surveillance and supportive care.

Indexed as

cognitive impairmentelderly patient caregait disturbancenormal pressure hydrocephalusurinary incontinence (ui)

Identifiers

PMID41141176
PMCPMC12548762

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.