ArticleCureus2025
Mitral Valve Aneurysm With Perforation Resulting in Severe Mitral Regurgitation Secondary to Infective Endocarditis: A Report of a Rare Case.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Mitral valve aneurysm (MVA) is a localised bulge of the mitral leaflet. Weakening of the mitral leaflet may be induced by infective endocarditis (IE), rheumatic disease, and connective tissue disorders like osteogenesis imperfecta, Marfan syndrome, and pseudoxanthoma elasticum. Complications of MVA include expansion, perforation, and regurgitation. IE, characterised by inflammation of endocardium, has significant morbidity and mortality. We report a case of mitral valve aneurysm with perforation in the setting of IE, diagnosed by transesophageal echocardiography (TEE). A 72-year-old male with multiple comorbidities presented with fluid overload and renal dysfunction. He had been previously admitted for sepsis, wet gangrene, and atrial fibrillation, which were treated medically. Blood cultures at the time grew
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