Evidence map›Paper›PMID 41141016›Full record

ArticleCureus2025

Transfusion-Related Acute Lung Injury Detected by Perioperative Lung Ultrasound: Early Recognition With Point-of-Care Ultrasound (POCUS).

Aaron M Kessler, Arpan Kohli, Grant Neely

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aaron M KesslerAnesthesiology, West Virginia University School of Medicine, Morgantown, USA.
Arpan KohliAnesthesiology, West Virginia University School of Medicine, Morgantown, USA.
Grant NeelyAnesthesiology, West Virginia University School of Medicine, Morgantown, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transfusion-related acute lung injury (TRALI) is a rare but potentially life-threatening transfusion reaction characterized by acute hypoxemia and non-cardiogenic pulmonary edema within six hours of transfusion. We report the case of a 20-year-old female patient who developed acute hypoxemia approximately 1.5 hours after receiving one unit of packed red blood cells (PRBCs) during dilation and suction curettage under general anesthesia. Postoperatively, she experienced dyspnea, oxygen desaturation, and coarse bilateral breath sounds. Point-of-care ultrasound (POCUS) demonstrated multiple bilateral B-lines without evidence of pneumothorax, effusion, or cardiac dysfunction, raising suspicion for non-cardiogenic pulmonary edema. Computed tomography (CT) further revealed bilateral ground-glass opacities and septal thickening, supporting the diagnosis of TRALI. The patient required supplemental oxygen and demonstrated rapid clinical improvement. This case highlights the clinical utility of lung POCUS as an early diagnostic adjunct for differentiating TRALI from other causes of acute postoperative respiratory decompensation.

Indexed as

acute respiratory distress syndrome (ards)anesthesiologycomplications of red blood cell transfusioncritical carelung ultrasoundpoint-of-care-ultrasoundtransfusion medicinetransfusion-related acute lung injury

Identifiers

PMID41141016
PMCPMC12553504

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.