ArticleCureus2025
Venous Cannulation Site Stenosis and Risk of Recurrence: A New Hypothesis.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMaintenance of vascular access (VA) patency in hemodialysis (HD) can be challenging and may require multiple endovascular interventions. Changes in local hemodynamics and vessel wall injury caused by needle cannulation are related to a higher risk of neointimal hyperplasia and stenotic lesions. We proposed to analyze the incidence of venous cannulation site stenosis (VCSS) requiring angioplasty and the need for reintervention.
methodsThis is a retrospective cohort single-center study conducted on 431 HD patients with arteriovenous fistulas (AVFs) subjected to stenosis correction in 2022. Descriptive and comparative statistical analyses were performed.
resultsA total of 544 procedures on 438 AVFs were analyzed. The median age was 72 (62-80) years. The most commonly intervened autologous VA was the brachiocephalic (53.4%; n = 234), and of all AVFs, 19.6% (n = 86) were intervened on more than once. The most common stenosis locations were in not otherwise specified (NOS) venous segments (32.4%; n = 176), followed by cephalic arch (30.9%; n = 168) and venous cannulation sites (25.6%; n = 139). Of the AVFs with VCSS identified on first intervention (n = 98), 35.7% (n = 35) had to be reintervened, of which 71.4% (n = 25) recurred on the same site. The intervention on this kind of stenosis is more likely to occur in proximal AVF (p < 0.001) and has a higher risk of needing reintervention (p = 0.004).
conclusionsThere seems to be a relation between VCSS and risk for restenosis, highlighting the role of needle cannulation techniques (including length of cannulation tunnel) and blood flow at cannulation sites in the development of stenotic lesions.
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Registered trials
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