Evidence map›Paper›PMID 41141002›Full record

ArticleCureus2025

Paraneoplastic Dermatomyositis as the Presenting Symptom of Tonsillar Squamous Cell Carcinoma: A Case Report.

Max Vogel, Abigail Kammerer, Raj Dwivedi, Karyn Dyehouse, Terese Howes

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Max VogelOncology, University of South Carolina School of Medicine Greenville, Greenville, USA.
Abigail KammererOncology, University of South Carolina School of Medicine Greenville, Greenville, USA.
Raj DwivediOncology, University of South Carolina School of Medicine Greenville, Greenville, USA.
Karyn DyehouseOncology, University of South Carolina School of Medicine Greenville, Greenville, USA.
Terese HowesRadiation Oncology, University of South Carolina School of Medicine Greenville, Greenville, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dermatomyositis is an autoimmune multisystem disorder affecting skin and skeletal muscle that often presents with symmetric proximal muscle weakness and cutaneous manifestations such as rash. Dermatomyositis may present as a paraneoplastic phenomenon before, concurrent with, or after the diagnosis of cancer. Several cancers, including lung, breast, stomach, ovary, and kidney carcinoma, are frequently noted as the trigger for the development of paraneoplastic dermatomyositis. Less common, nasopharyngeal carcinomas have been associated with paraneoplastic dermatomyositis. Even more rare, we present a case of a 61-year-old male found to have dermatomyositis as the presenting symptom of p16-positive squamous cell carcinoma of the oropharynx involving the left tonsil with unilateral neck involvement and solitary lung metastasis. This case highlights a rare presentation of paraneoplastic dermatomyositis and emphasizes the importance of including p16+ tonsillar carcinoma in the differential diagnosis and screening protocols following the discovery of dermatomyositis.

Indexed as

dermatomyositishead and neck canceroropharyngeal cancerparaneoplastic syndrometonsillar cancer

Identifiers

PMID41141002
PMCPMC12547066

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.