ArticleCureus2025
Impact of Rhegmatogenous Retinal Detachment Repair on Macular Microvascular Changes Detected by Optical Coherence Tomography Angiography (OCTA).
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose Rhegmatogenous retinal detachment (RRD) occurs when the sensory retina separates from the retinal pigment epithelium (RPE) due to a retinal break. Pars plana vitrectomy (PPV) with gas or silicone oil tamponade is the primary surgical approach for RRD repair. This study evaluates microvascular changes in eyes undergoing PPV for RRD using optical coherence tomography angiography (OCTA) and compares outcomes between macula-on and macula-off cases. Methods This retrospective study included 45 patients (21 macula-on, 24 macula-off) who underwent RRD repair. OCTA was used to assess central retinal thickness (CRT), vessel density in the superficial (sVD) and deep capillary plexus (dVD), and the foveal avascular zone (FAZ). Comparisons were made between affected and fellow eyes, as well as between macula-on and macula-off cases. Results CRT was significantly different between macula-on and macula-off groups (p < 0.01). A weak but significant correlation was found between best-corrected visual acuity (BCVA) and FAZ area (r = 0.21, p = 0.018). Inferior detachments had lower dVD (32.16 ± 5.22%) than other quadrants (p < 0.05). dVD was reduced in affected eyes compared to fellow eyes in both macula-on (p = 0.01) and macula-off groups (p < 0.01), while sVD decreased significantly only in macula-off cases (p = 0.03). Conclusion RRD repair significantly impacts retinal microvasculature, particularly dVD reduction in macula-off cases and inferior RRDs. The correlation between FAZ enlargement and BCVA suggests microvascular alterations influence visual recovery. These findings highlight the need for further investigation into vascular recovery strategies after RRD repair.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.