ArticleCureus2025
Osmotic Demyelination Syndrome Associated With Severe Acute Hypernatremia Secondary to Poorly Controlled Central Diabetes Insipidus.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osmotic demyelination syndrome is a rare disorder caused by destruction of the myelin sheath, particularly in the pontine region, generally secondary to rapid osmotic variations. Osmotic demyelination syndrome due to hypernatremia is rarely described in the literature. The prognosis has improved thanks to a better understanding of its pathophysiology and advances in diagnosis and therapy. In this article, we report the case of centropontine and extrapontine myelinolysis associated with severe acute hypernatremia at 181 mEq/l secondary to abrupt discontinuation of desmopressin prescribed in the setting of central diabetic insipidus complicating pituitary surgery in a 58-year-old man. The evolution was favorable after reintroduction of desmopressin and correction of hypernatremia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.