Evidence map›Paper›PMID 41140961›Full record

ArticleBioactive materials2026

Single chiral center epimerization-modulated multi-carrier-free oral hydrogel for remolding inflammatory microenvironment via PI3K/Akt/NF-κB and MAPK signaling pathways.

Wenmin Pi, Gen Li, Hailing Qiu, Yihang Zhao, Yaozhi Zhang, Xinru Tan, Jihui Lu, Zhijia Wang, Xuemei Huang, Penglong Wang

Abstract read
In one paragraph

Article in Bioactive materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wenmin PiSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102488, China.
Gen LiSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102488, China.
Hailing QiuSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102488, China.
Yihang ZhaoSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102488, China.
Yaozhi ZhangSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102488, China.
Xinru TanSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102488, China.
Jihui LuSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102488, China.
Zhijia WangSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102488, China.
Xuemei HuangSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102488, China.
Penglong WangSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102488, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The self-assembly of biomolecules with chiral centers in nature has garnered significant attention due to its biomedical potential. However, how single chiral center epimerization influences molecular co-assembly remains unclear. This study explored natural epimers 18

Indexed as

Multi-carrier-free oral hydrogelRemold inflammatory microenvironmentSingle chiral center epimers

Identifiers

PMID41140961
PMCPMC12546808

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.